Hereditary Hypertension: Difference between revisions
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== Introduction == | == Introduction == | ||
Hypertension (HPT) is known to be a complex heterogeneous condition controlled by many genes. The factors that regulate HPT have a strong genetic component, but the precise genes involved in HTN development are not well known. The drug therapy available for HPT do not always prevent the occurrence of high BP. Novel drug treatment approaches are needed that use genetic | Hypertension (HPT) is known to be a complex heterogeneous condition controlled by many genes. The factors that regulate HPT have a strong genetic component, but the precise genes involved in HTN development are not well known. The drug therapy available for HPT do not always prevent the occurrence of high BP. | ||
* 18 genotype/phenotype groups have been found to be linked nearly 1/2 of the primary HPT populations, giving a pathway to discover treatment/prevention better individual primary HPT treatments.<ref>Manosroi W, Williams GH. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936319/ Genetics of human primary hypertension: focus on hormonal mechanisms]. Endocrine reviews. 2019 Jun;40(3):825-56.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936319/ (7.5.2024)</ref> | |||
* Novel drug treatment approaches are needed that use this genetic approach and personalized medicine.<ref>Pandey KN. [https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.124.22072 Genetic and Epigenetic Mechanisms Regulating Blood Pressure and Kidney Dysfunction.] Hypertension. 2024 Mar 28.Available:https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.124.22072 (accessed 7.5.2024)</ref> | |||
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Revision as of 02:57, 7 May 2024
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton
Introduction[edit | edit source]
Hypertension (HPT) is known to be a complex heterogeneous condition controlled by many genes. The factors that regulate HPT have a strong genetic component, but the precise genes involved in HTN development are not well known. The drug therapy available for HPT do not always prevent the occurrence of high BP.
- 18 genotype/phenotype groups have been found to be linked nearly 1/2 of the primary HPT populations, giving a pathway to discover treatment/prevention better individual primary HPT treatments.[1]
- Novel drug treatment approaches are needed that use this genetic approach and personalized medicine.[2]
Sub Heading 2[edit | edit source]
Sub Heading 3[edit | edit source]
Resources[edit | edit source]
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References[edit | edit source]
- ↑ Manosroi W, Williams GH. Genetics of human primary hypertension: focus on hormonal mechanisms. Endocrine reviews. 2019 Jun;40(3):825-56.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936319/ (7.5.2024)
- ↑ Pandey KN. Genetic and Epigenetic Mechanisms Regulating Blood Pressure and Kidney Dysfunction. Hypertension. 2024 Mar 28.Available:https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.124.22072 (accessed 7.5.2024)
