Hereditary Hypertension
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton
Introduction[edit | edit source]
Hypertension (HPT) is known to be a complex heterogeneous condition controlled by many genes. The factors that regulate HPT have a strong genetic component, but the precise genes involved in HTN development are not well known. The drug therapy available for HPT do not always prevent the occurrence of high BP.
- 18 genotype/phenotype groups have been found to be linked nearly 1/2 of the primary HPT populations, giving a pathway to discover treatment/prevention better individual primary HPT treatments.[1]
- Novel drug treatment approaches are needed that use this genetic approach and personalized medicine.[2]
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Resources[edit | edit source]
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References[edit | edit source]
- ↑ Manosroi W, Williams GH. Genetics of human primary hypertension: focus on hormonal mechanisms. Endocrine reviews. 2019 Jun;40(3):825-56.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936319/ (7.5.2024)
- ↑ Pandey KN. Genetic and Epigenetic Mechanisms Regulating Blood Pressure and Kidney Dysfunction. Hypertension. 2024 Mar 28.Available:https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.124.22072 (accessed 7.5.2024)
