Evaluation of Ankylosing Spondylitis Quality of Life

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Top Contributors - Jessica Pun and Kim Jackson  

Objective[edit | edit source]

The Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL) is a patient reported outcome measure developed by Haywood et al. [1]It consists of 20-item questionnaire assessing four domains of physical function, disease activity, emotional well-being and social participation.

Intended Population[edit | edit source]

The EASi-AOL was designed to use in people with Ankylosing Spondylitis (AS).

Method of Use[edit | edit source]

The EASi-QOL is a self-reported questionnaire. Patients select an answer from the option that best described their physical function on the day of questionnaire administration. For the domains of disease activity, emotional well-being and social participation, patient give their response based on their average over the past week. Each question scores from 0-4, and a lower score indicates better quality of life.

Single missing answer in a domain will be scored as the mean of the questions answered in that particular domain. The domain cannot be scored if more than one question is missing in a domain.

Evidence[edit | edit source]

Reliability[edit | edit source]

High test-retest reliability were reported with intraclass correlation coefficients (ICC) at 0.93 for the physical function domain, 0.88 for the disease activity domain, 0.90 for the emotional well-being domain and 0.90 social participation domain. [1]

Validity[edit | edit source]

High correlations between EASi-QOL domains and the Short Form Health Survey 36 (SF-36), EuroQol- 5 Dimension (EQ-5D) and other AS-specific questionnaire of related constructs including the Bath AS Disease Activity Index (BASDAI) and the Bath AS Functional Index (BASFI).

Responsiveness[edit | edit source]

Based on observational and intervention studies, evidence of responsiveness was reported to be similar to comparative AS-specific and generic measures [2].

References[edit | edit source]

  1. 1.0 1.1 1.2 Haywood KL, Garratt AM, Jordan KP, Healey EL, Packham JC. Evaluation of ankylosing spondylitis quality of life (EASi-QoL): reliability and validity of a new patient-reported outcome measure. The Journal of rheumatology. 2010 Oct 1;37(10):2100-9.
  2. Packham JC, Jordan KP, Haywood KL, Garratt AM, Healey EL. Evaluation of Ankylosing Spondylitis Quality of Life questionnaire: responsiveness of a new patient-reported outcome measure. Rheumatology. 2012 Apr 1;51(4):707-14.