End Organ
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton
Introduction[edit | edit source]
An end organ is the last organ affected in a chain of events, for instance a disease process.
Examples are the liver, brain, kidney or heart, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.
Detection[edit | edit source]
Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.
Classical pointers for end organ damage include:
- Stoke, vascular and hemorrhagic
- Retinopathy
- Coronary heart disease/myocardial infarction and heart failure
- Proteinuria
- Renal failure
- Atherosclerotic change eg stenoses and aneurysms in the blood vessels.[1]
Risk Factors[edit | edit source]
Many and varied and include:
- Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
- Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
- Type 2 diabetes mellitus is associated with target organ damage
Viewing[edit | edit source]
Watch this 1 mi nute video with information tables regarding "Assessing damage to major organs due to hypertension".
References[edit | edit source]
- ↑ Schmieder RE. End organ damage in hypertension. Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)
- ↑ MediBuddy - Your Health Friend. End organ damage in Hypertension | Hypertension Update | Dr Adrija | CME Session | MediBuddy. Available from: https://www.youtube.com/watch?v=WVFbsgg1c_Q [last accessed 9.5.2024]
