Effects of Ageing on Bone: Difference between revisions

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'''Lead Editors'''    
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== Clinically Relevant Anatomy<br>  ==
== Aging<br>  ==
 
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== Mechanism of Injury / Pathological Process<br>  ==
 
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== Clinical Presentation  ==
Aging refers to the physiological changes that occur in the human body from the attainment of adulthood, and ending in death. These changes involve a decline of biological functions, and are accompanied by psychological, behavioural, and other changes. Some of these changes are quite obvious, while others are subtle.<ref name="brit">http://www.britannica.com/EBchecked/topic/1354293/human-aging</ref> <br>


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== Diagnostic Procedures ==
== The Aging Bone<br> ==


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Bones undergo a lifelong process of remodeling – mature bone tissue is removed and new bone tissue is formed. Bone remodeling is a highly regulated process that maintains a balance between bone resorption and formation, thus maintaining skeletal integrity.<ref name="remodel">Hadjidakis DJ, Androulakis II. Bone Remodeling. Ann N Y Acad Sci. 2006 Dec;1092:385-96.</ref><br>  


== Outcome Measures  ==
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This balance changes with increasing age, resulting in loss of bone tissue. The aging bone has reduced mineral content, and is prone to osteoporosis – a condition in which bones are less dense, more fragile, and prone to fractures.<ref name="aaos">http://orthoinfo.aaos.org/topic.cfm?topic=A00191</ref>


== Management / Interventions<br> ==
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== Effects of Changes in Aging Bone<ref>http://www.nlm.nih.gov/medlineplus/ency/article/004015.htm</ref>  ==


== Differential Diagnosis<br> ==
*Osteoporosis is a common problem among older people, especially post-menopausal women, and is a major cause of hip fractures in the elderly.
*<span style="line-height: 1.5em;">Reduced bone density of the vertebrae, combined with the loss of fluid in intervertebral discs, result in a curved and shortened trunk.</span>  
*This reduced bone density, and resulting poor posture, leads to pain, reduced mobility, and other musculoskeletal problems.


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== Key Evidence ==
== Prevention<ref>http://www.nlm.nih.gov/medlineplus/ency/article/000360.htm</ref> ==


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Exercise is important for preserving bone density, however care must be taken to avoid high-impact exercises and exercises that present the risk of falling. Useful exercises include:


== Resources <br>  ==
*Weight-bearing exercises e.g. walking
*Strengthening exercises using free weights, elastic bands
*Balance exercises e.g. tai chi


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== Case Studies  ==
A healthy diet, including adequate dosage of Vitamin D and Calcium, is also useful for preserving bone mass.<br>


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== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed])  ==
== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed])  ==
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== References  ==
== References<br> ==
 
References will automatically be added here, see [[Adding References|adding references tutorial]].


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Revision as of 01:18, 26 June 2014

Original Editor - Your name will be added here if you created the original content for this page.

Lead Editors  


Aging
[edit | edit source]

Aging refers to the physiological changes that occur in the human body from the attainment of adulthood, and ending in death. These changes involve a decline of biological functions, and are accompanied by psychological, behavioural, and other changes. Some of these changes are quite obvious, while others are subtle.[1]


The Aging Bone
[edit | edit source]

Bones undergo a lifelong process of remodeling – mature bone tissue is removed and new bone tissue is formed. Bone remodeling is a highly regulated process that maintains a balance between bone resorption and formation, thus maintaining skeletal integrity.[2]


This balance changes with increasing age, resulting in loss of bone tissue. The aging bone has reduced mineral content, and is prone to osteoporosis – a condition in which bones are less dense, more fragile, and prone to fractures.[3]


Effects of Changes in Aging Bone[4][edit | edit source]

  • Osteoporosis is a common problem among older people, especially post-menopausal women, and is a major cause of hip fractures in the elderly.
  • Reduced bone density of the vertebrae, combined with the loss of fluid in intervertebral discs, result in a curved and shortened trunk.
  • This reduced bone density, and resulting poor posture, leads to pain, reduced mobility, and other musculoskeletal problems.


Prevention[5][edit | edit source]

Exercise is important for preserving bone density, however care must be taken to avoid high-impact exercises and exercises that present the risk of falling. Useful exercises include:

  • Weight-bearing exercises e.g. walking
  • Strengthening exercises using free weights, elastic bands
  • Balance exercises e.g. tai chi


A healthy diet, including adequate dosage of Vitamin D and Calcium, is also useful for preserving bone mass.


Recent Related Research (from Pubmed)[edit | edit source]

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References
[edit | edit source]