Drooling In Parkinsons Disease

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Introduction[edit | edit source]

Drooling in Parkinson’s disease (PD) is an many times disregarded however it is an important non-motor symptom that impacts the patient's quality of life, [1] having negative physical and psychosocial consequences for patients.[2] In relatively advanced patients with PD, drooling occurs in over 30% of patients, with dysphagia occurring with greater frequency in these patients[1]. The precise pathophysiological mechanism of drooling in PD is not clear, however excessive drooling is shown to be associated with higher burdens of non-motor symptoms and greater motor fluctuations of motor symptoms and bradykinesia[3].

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References[edit | edit source]

  1. 1.0 1.1 van Wamelen DJ, Leta V, Johnson J, Ocampo CL, Podlewska AM, Rukavina K, Rizos A, Martinez-Martin P, Chaudhuri KR. Drooling in Parkinson’s disease: prevalence and progression from the non-motor international longitudinal study. Dysphagia. 2020 Dec;35:955-61 .Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669801/ (accessed 9.11.2023)
  2. Srivanitchapoom P, Pandey S, Hallett M. Drooling in Parkinson's disease: a review. Parkinsonism & related disorders. 2014 Nov 1;20(11):1109-18.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252747/ (accessed 9.11.2023)
  3. Polychronis S, Nasios G, Dardiotis E, Messinis L, Pagano G. Pathophysiology and Symptomatology of Drooling in Parkinson’s Disease. InHealthcare 2022 Mar 11 (Vol. 10, No. 3, p. 516). MDPI.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951596/ (accessed 9.11.2023)