Double Crush Syndrome

Introduction

• The double crush hypothesis was first formulated in 1973 and states that axons that have been compressed at one site become especially susceptible to damage at another site.
  
• This theory was originally described by Upton (1973) in a study of 115 patients.
• The existence of double crush syndrome was further substantiated by Massey's (1981) study of nineteen cases of carpal tunnel syndrome co-existing with a cervical radiculopathy.