Chemotherapy-Induced Peripheral Neuropathy (CIPN): Difference between revisions

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== Introduction ==
== Introduction ==
Chemotherapy-induced peripheral neuropathy (CIPN) commonly occurs as an adverse event following chemotherapy.CIPN can  have an effect on the sensory, motor and/or autonomic nerves<ref name=":0">Burgess J, Ferdousi M, Gosal D, Boon C, Matsumoto K, Marshall A, Mak T, Marshall A, Frank B, Malik RA, Alam U. Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment. Oncology and therapy. 2021 Dec 1:1-66.Available:https://pubmed.ncbi.nlm.nih.gov/33490836/ (accessed 18.8.2023)</ref>. Currently there is no gold standard for diagnosis, no proven ways to lessen or stop this condition and treatment strategies need be addressed.<ref name=":0" />Physiotherapy, in the form of exercise therapy, has been shown to have a role in reducing symptoms in CIPN<ref>Jesson T, Runge N, Schmid AB. [https://pubmed.ncbi.nlm.nih.gov/33490836/ Physiotherapy for people with painful peripheral neuropathies: a narrative review of its efficacy and safety.] Pain Reports. 2020 Sep;5(5).Available: https://pubmed.ncbi.nlm.nih.gov/33490836/<nowiki/>(accessed 18.8.2023)</ref>.
Chemotherapy-induced peripheral neuropathy (CIPN) commonly occurs as an adverse event following chemotherapy.CIPN can  have an effect on the sensory, motor and/or autonomic nerves<ref name=":0">Burgess J, Ferdousi M, Gosal D, Boon C, Matsumoto K, Marshall A, Mak T, Marshall A, Frank B, Malik RA, Alam U. Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment. Oncology and therapy. 2021 Dec 1:1-66.Available:https://pubmed.ncbi.nlm.nih.gov/33490836/ (accessed 18.8.2023)</ref>.  
 
Currently there is no gold standard for diagnosis, no proven ways to lessen or stop this condition and treatment strategies need be addressed.<ref name=":0" />
 
CIPN regularly impacts chemotherapy, occasionally  requiring the dose to be reduced or treatment ceased, effecting survival. Around 30% of patients will still have CIPN a year, or more post chemotherapy<ref>Colvin LA. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499732/ Chemotherapy-induced peripheral neuropathy (CIPN): where are we now?]. Pain. 2019 May;160(Suppl 1):S1.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499732/ (accessed 19.8.2023)</ref>.
 
Physiotherapy, in the form of exercise therapy, has been shown to have a role in reducing symptoms in CIPN<ref>Jesson T, Runge N, Schmid AB. [https://pubmed.ncbi.nlm.nih.gov/33490836/ Physiotherapy for people with painful peripheral neuropathies: a narrative review of its efficacy and safety.] Pain Reports. 2020 Sep;5(5).Available: https://pubmed.ncbi.nlm.nih.gov/33490836/<nowiki/>(accessed 18.8.2023)</ref>.


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Revision as of 02:28, 19 August 2023

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Introduction[edit | edit source]

Chemotherapy-induced peripheral neuropathy (CIPN) commonly occurs as an adverse event following chemotherapy.CIPN can have an effect on the sensory, motor and/or autonomic nerves[1].

Currently there is no gold standard for diagnosis, no proven ways to lessen or stop this condition and treatment strategies need be addressed.[1]

CIPN regularly impacts chemotherapy, occasionally requiring the dose to be reduced or treatment ceased, effecting survival. Around 30% of patients will still have CIPN a year, or more post chemotherapy[2].

Physiotherapy, in the form of exercise therapy, has been shown to have a role in reducing symptoms in CIPN[3].

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Resources[edit | edit source]

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References[edit | edit source]

  1. 1.0 1.1 Burgess J, Ferdousi M, Gosal D, Boon C, Matsumoto K, Marshall A, Mak T, Marshall A, Frank B, Malik RA, Alam U. Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment. Oncology and therapy. 2021 Dec 1:1-66.Available:https://pubmed.ncbi.nlm.nih.gov/33490836/ (accessed 18.8.2023)
  2. Colvin LA. Chemotherapy-induced peripheral neuropathy (CIPN): where are we now?. Pain. 2019 May;160(Suppl 1):S1.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499732/ (accessed 19.8.2023)
  3. Jesson T, Runge N, Schmid AB. Physiotherapy for people with painful peripheral neuropathies: a narrative review of its efficacy and safety. Pain Reports. 2020 Sep;5(5).Available: https://pubmed.ncbi.nlm.nih.gov/33490836/(accessed 18.8.2023)