Complex Regional Pain Syndrome (CRPS)
Original Editors - Yves Hubar
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Search Strategy[edit | edit source]
Literature was found on pubmed and the vub v-spaces system.
Definition/Description[edit | edit source]
The international association for the study of pain defines CRPS as a collection of locally occurring painful conditions, usually following traumatic injury, which tends to express itself distally and exceeds the expected pain of the original trauma and usually results in significant motor deficit. [1]
CRPS is subdivided into type I and type II CRPS.
Type I CRPS signifies that no peripheral nerve injury can be linked to the condition, while type II signifies that the condition results from a peripheral nerve injury. [2]
Clinically Relevant Anatomy[edit | edit source]
CRPS can take place in any body part, but the wrist is most frequently affected after fractures.
An important aspect of the disease is the occurance of vascular disturbances. Mostly affected are primary small vessels, causing an impact on microcirculation, skin temperature and clinical appearance of the limb.
A paper described the changes in microcirculation as an increase in the number of capillaries, endothelial swelling and changes in the vessel luminal wall.[2]
According to a review, the acute stage features inhibited sympathetic vasoconstriction and exaggerated neurogenic inflammation, whereas the cold stage features vasoconstriction and endothelial disfunction or vascular hyperreactivity while neurogenic inflammation is less severe.[3]
Epidemiology /Etiology[edit | edit source]
Characteristics/Clinical Presentation[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Diagnostic Procedures[edit | edit source]
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Outcome Measures[edit | edit source]
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Examination[edit | edit source]
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Medical Management
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Physical Therapy Management
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Key Research[edit | edit source]
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Resources
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Clinical Bottom Line[edit | edit source]
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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- ↑ L.Verbruggen. Reumatologie. Dienst Uitgaven VUB 2011
- ↑ 2.0 2.1 Groeneweg G, Huygen FJ, Coderre TJ, Zijlstra FJ. Regulation of peripheral blood flow in Complex Regional Pain Syndrome: clinical implication for symptomatic relief and pain management. BMC Musculoskelet Disord. 2009 Sep 23;10:116. (Level A1)
- ↑ Wasner G. Vasomotor Disturbances in Complex Regional Pain Syndrome—A Review. Pain Med. 2010 Aug;11(8):1267-73. (Level C)
