Infantile Colic

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Introduction[edit | edit source]

Infantile colic is described as excessive crying with no clear cause in infants who otherwise present as healthy. Its presentation is widely reported - as little as 3% or up to 40% of infants worldwide. An Australian journal recently reported 20%, while the Singapore Medical Journal reported 40% presentation in the healthcare sector.[1][2][3]

In general, it appears that infant colic is one of the most common causes for hospital emergency visits in the first few months of life.[1]

It is generally described as a self-limiting condition, resolving after three to four months of life.[2]

Pathological Process[edit | edit source]

While colic implies a gastrointestinal origin, research into conditions relating to the gastrointestinal system and the prevalence of colic has found inconclusive or weak associations.[1][3][2]

Among the topics researched, the following were most prevalent:

  • Microbiota and inflammatory markers (both in the gut and systemically)
  • Lactose intolerance
  • Gastro-oesophageal reflux

Other possible causes have included:[4]

  • Increased serotonin secretion
  • Poor feeding technique
  • Maternal smoking or nicotine replacement therapy

Clinical Presentation[edit | edit source]

add text here relating to the clinical presentation of the condition

Diagnostic Procedures[edit | edit source]

add text here relating to diagnostic tests for the condition

Outcome Measures[edit | edit source]

add links to outcome measures here (see Outcome Measures Database)

Management / Interventions
[edit | edit source]

Because of its benign nature, the first recommendation for treatment is parental education, including the aspect that colic is benign and self-limiting. In addition, supportive resources can also be offered.[4]

Medical Management[edit | edit source]

Probiotics

Medications

Dietary Modifications

Physical Therapies

Herbal Supplements



Differential Diagnosis
[edit | edit source]

Conditions that should be checked for unexplained crying in infants include:[4]

  • Hirschsprung disease
  • Incarcerated hernia or testicular torsion
  • Child abuse
  • Gastroesophageal reflux
  • Pyloric stenosis
  • Anal fissure
  • Corneal abrasion
  • Cow's milk allergy
  • Hair tourniquet syndrome
  • Inadequate bottle feeding
  • Inadequate breast feeding

The above causes are detailed in regards to findings, physical examinations, historical clues and diagnostic testing here.

Red flags which point to other more serious conditions are:[4]

  • Distended abdomen
  • Fever
  • Lethargy

Details are found here.

Resources
[edit | edit source]

add appropriate resources here

References[edit | edit source]

  1. 1.0 1.1 1.2 Ellwood J, Draper-Rodi J, Carnes D. Comparison of common interventions for the treatment of infantile colic: a systematic review of reviews and guidelines. BMJ Open. 2020; 10 (2): e035405.
  2. 2.0 2.1 2.2 Sung V. Infantile colic. Australian prescriber. 2018 Aug;41(4):105.
  3. 3.0 3.1 Lam TM, Chan PC, Goh LH. Approach to infantile colic in primary care. Singapore medical journal. 2019 Jan;60(1):12.
  4. 4.0 4.1 4.2 4.3 Johnson JD, Cocker K, Chang E. Infantile colic: recognition and treatment. American family physician. 2015 Oct 1;92(7):577-82.