Proliferative Myositis
Original Editors - Billie Rehberg from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
Proliferative myositis (PM) is a benign tumor which grows in skeletal muscle[1]. It is often mistaken for sarcomas (especially rhabdomyosarcoma)[2]. While etiology is unknown, it may result from injury to the muscle, fascia, or vasculature (resulting in ischemia) of the associated area[3]. Median age of onset is 50 years[4], with rare cases reported in children[5]
- Rapidly enlarging, solid tumor within skeletal muscle
- Localized inflammation
- No lymph node enlargement
- No significant laboratory results
Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
While etiology is unknown, PM may result from injury to the muscle, fascia, or vasculature (resulting in ischemia) of the associated area[3].
Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
Surgical excision (recurrence following excision is rare)[5]
Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[4][2][5][edit | edit source]
- Myositis Ossificans
- Neoplasms (especially rhabdomyosarcomas)
- Proliferative fasciitis
- Nodular fasciitis
- Fibromatosis
- Ganglioneuroblastoma or ganglioneuroma
Case Reports/ Case Studies[edit | edit source]
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Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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- ↑ Fauser C, Nahrig J, Niedermeyer H, Arnold W. Proliferative myositis: a rare pseudomalignant tumor of the head and neck. Archives of Otolaryngology - Head & Neck Surgery [serial on the Internet]. (2008, Apr), [cited March 16, 2011]; 134(4): 437-440. Available from: CINAHL with Full Text.
- ↑ 2.0 2.1 Meis J, Enzinger F. Proliferative fasciitis and myositis of childhood. The American Journal Of Surgical Pathology [serial on the Internet]. (1992, Apr), [cited March 16, 2011]; 16(4): 364-372. Available from: MEDLINE.
- ↑ 3.0 3.1 Dent C, DeBoom G, Hamlin M. Proliferative myositis of the head and neck. Report of a case and review of the literature. Oral Surgery, Oral Medicine, And Oral Pathology [serial on the Internet]. (1994, Sep), [cited March 16, 2011]; 78(3): 354-358. Available from: MEDLINE.
- ↑ 4.0 4.1 Mulier S, Stas M, Delabie J, Lateur L, Gysen M, De Wever I, et al. Proliferative myositis in a child. Skeletal Radiology [serial on the Internet]. (1999, Dec), [cited March 16, 2011]; 28(12): 703-709. Available from: MEDLINE.
- ↑ 5.0 5.1 5.2 Stanford School of Medicine. Proliferative Myositis. Available at: http://surgpathcriteria.stanford.edu/softfib/proliferative_myositis/printable.html. Accessed on April 4, 2011
== Prevalence ==fckLRfckLRAs of 2008, only about 100 published cases existed, 25% of which dealt with proliferative myositis of the head and neck musculature<ref name="Fauser et. al" />.fckLRfckLR== Characteristics/Clinical Presentation ==fckLRfckLRSigns and symptoms of PM:<ref name="Fauser et. al" /><ref name="Meis et. al" /><ref name="Gysen et. al">Gysen M, Stroobants S, Mortelmans L. Proliferative myositis: a case of a pseudomalignant process. Clinical Nuclear Medicine [serial on the Internet]. (1998, Dec), [cited March 16, 2011]; 23(12): 836-838. Available from: MEDLINE. Cite error: Invalid
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