Muscle Repair
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Top Contributors - Lucinda hampton
Introduction[edit | edit source]
Skeletal muscle repair requires the activation of satellite cells, which are the residential muscle stem cells. The repair/regeneration is a highly coordinated process, involving cell-cell, cell matrix and extracellular matrix interactions. Immune, fibrotic, vascular and myogenic cells all play a role in the three phases of muscle repair/ regeneration. These phases
- Destruction phase with the initial inflammatory response
- Regeneration phase with activation and proliferation of satellite cells
- Remodelling phase with maturation of the regenerated myofibers
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