Hormone Replacement Therapy

Benefits of hormone replacement therapy[edit | edit source]

  1. Menopausal symptoms: HRT is widely used for the established indications of menopausal symptoms.
  2. Osteoporotic fractures: An older population with severe osteoporosis might have enjoyed greater protection from fractures with HRT. Some studies also found out the uses HRT reduces vertebral and hip fractures.
  3. Cardiovascular disease: HRT is used high cholesterol levels and for coronary heart disease. Hence, for primary prevention of cardiovascular disease.
  4. Healthy living: Women who use HRT have a significantly decreased risk of disease and death than women who do not.
  5. Breast cancer: The risk of metastases among breast cancer patients who had used HRT was significantly decreased; this suggests that these cancers were localized to the breast and potentially had a better prognosis.
  6. Colorectal cancer: studies suggested that estrogen reduces the risk of colorectal cancer. While other studies found out that HRT bring about protection of colorectal cancer with increased in duration of use.
  7. Brain: some studies have found out that may have effect on the brain. A beneficial effect on verbal memory, vigilance, motor speed, and reasoning on symptomatic women.

Harms of hormone replacement therapy.[edit | edit source]

Harms of HRT include coronary heart disease, stroke, and thromboembolism (especially during early use). The risk of breast cancer and cholecystitis increases with longer use.[1]

References[edit | edit source]

  1. Grimes DA, Lobo RA. Perspectives on the Women’s Health Initiative trial of hormone replacement therapy. Obstetrics & Gynecology. 2002 Dec 1;100(6):1344-53.