Hormone Replacement Therapy

Benefits of hormone replacement therapy[edit | edit source]

  1. Menopausal symptoms: HRT is widely used for the established indications of menopausal symptoms. • Osteoporotic fractures: An older population with severe osteoporosis might have enjoyed greater protection from fractures with HRT. Some studies also found out the uses HRT reduces vertebral and hip fractures. • Cardiovascular disease: HRT is used high cholesterol levels and for coronary heart disease. Hence, for primary prevention of cardiovascular disease. • Healthy living: Women who use HRT have a significantly decreased risk of disease and death than women who do not. • Breast cancer: The risk of metastases among breast cancer patients who had used HRT was significantly decreased; this suggests that these cancers were localized to the breast and potentially had a better prognosis. • Colorectal cancer: studies suggested that estrogen reduces the risk of colorectal cancer. While other studies found out that HRT bring about protection of colorectal cancer with increased in duration of use. • Brain: some studies have found out that may have effect on the brain. A beneficial effect on verbal memory, vigilance, motor speed, and reasoning on symptomatic women.

Harms of hormone replacement therapy.[edit | edit source]

Harms of HRT include coronary heart disease, stroke, and thromboembolism (especially during early use). The risk of breast cancer and cholecystitis increases with longer use.[1]

  1. Grimes DA, Lobo RA. Perspectives on the Women’s Health Initiative trial of hormone replacement therapy. Obstetrics & Gynecology. 2002 Dec 1;100(6):1344-53.