Nitrates
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton
Introduction[edit | edit source]
Nitrates are a class of medications that cause vasodilation. Nitrates exert their effects by dilating venous vessels, coronary arteries, and small arterioles; its maximal vasodilation is in the venous vessels.
- Nitrates are primarily indicated for the treatment of angina, where preferential venodilation causes pooling of blood, decreased preload, and ultimately decreased myocardial O2 demand.
- At high doses, nitrates can decrease afterload and may be used in hypertensive crises. The main adverse effects include headache, hypotension, and reflex tachycardia[1][2].
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References[edit | edit source]
- ↑ Lee PM, Gerriets V. Nitrates. InStatPearls [Internet] 2021 Jul 13. StatPearls Publishing.Available: https://www.ncbi.nlm.nih.gov/books/NBK545149/(accessed 7.4.2022)
- ↑ Lecturio Nitrates Available:https://www.lecturio.com/concepts/nitrates/ (accessed 7.4.2022)