Polycystic Ovarian Syndrome
Original Editors - Amanda Tieken from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
Polycysitc Ovarian Syndrome (PCOS), fomerly known as Stien-Leventhal Syndrome, is a disorder affecting the hormones of women of child bearing age.
Signs and symptoms include a collection of the following:
- Obesity1
- Hirsutism - hair growth in male pattern on the face, back, chest, lower abdomen, and inner thighs1
- Virilization - development of male features including balding of the frontal portion of the scalp, voice deepening, atophy of breast tissue, increased muscle mass, and clitoromegaly1
- Anovulation - failure of the ovaries to release an oocyte1
- Amenorrhea - abscence of a menstrual period in women of childbearing age1
Prevalence[edit | edit source]
PCOS affects 4-12% of childbearing aged women[1]
- 50% of these women have amenorrhea[2]
- 30% of these women have abnormal menstrual bleeding[2]
- 60% of these women are obese
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
- Type 2 diabetes
- Obesity (60%)
- Cardiovascular disease
- HTN
- Ovarian cancer
- Breast cancer
- Endometrial cancer
Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
There is no one difinitive test for the diagnosis of PCOS, but rather a ruling out of other possible disorders.
- Ultrasounography - abdominal or transvaginal
- Pelvic Examination
- Laproscopy
- Laboratory testing including CBC and CA-125
- Screenings for glucose intolerance
Goodman
Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Case Reports[edit | edit source]
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Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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