Psoriatic Arthritis
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
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Prevalence[edit | edit source]
- Occurs in 20% of persons that have psoriasis [1]
- Approximately 1% of U.S. population has psoriasis [1]
- 1%-3% of general population has psoriasis [2]
- Equal prevalence in both males and females [1]
- Can occur at any age but typically occurs between ages of 20-30 years old [2]
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities
- Psoriasis
- Presence of HLA-B27
Medications[edit | edit source]
- NSAIDS
- Local Corticosteroid Injections
Aggressive Cases
- DMARD Therapy with MTX, SSZ, and TNF-Beta Antagonists [1]
Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
- X-rays are often performed to detect bone erosion
- Blood work will be done to detect for the HLA-B27 since it is a common histocompatibility complex marker in people with psoriatic arthritis.
- A blood test for rheumatoid factor should be done to rule out rheumatoid arthritis
Causes[edit | edit source]
Psoriatic arthritis seems to have a genetic cause although the exact marker genes have not been identified. Having a first-degree realtive with psoriatic arthritis increases the likihood of contracting the disease by 80-90%.[1]
Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
- Osteoarthritis
- Rheumatoid Arthritis
- Gaut
- Mallet finger due to traumatic injury
Case Reports[edit | edit source]
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Recent Related Research (from Pubmed)[edit | edit source]
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[1]References [2][edit | edit source]
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