Lance-Adams Syndrome: Difference between revisions

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=== Introduction ===
=== Introduction ===
James W Adams and Raymond D Adams described this as a syndrome characterized by intentional myoclonus as a sequel to hypoxic encephalopathy.  Hypoxic encephalopathy can occur due to a cardiopulmonary arrest. Despite advanced practices in cardiopulmonary resuscitations, the outcomes after cardiopulmonary arrest seem to be poor and People after successful cardiopulmonary resuscitation often remain with some neurological deficits. LAS is reported very rarely less than 0.5 % in people who survives cardiac arrest. It is commonly confused with myoclonic status epilepticus (MSE) even though examination, imaging, level of disability and time of onset are very different <sup>(1).</sup>  
James W Adams and Raymond D Adams described this as a syndrome characterized by intentional myoclonus as a sequel to hypoxic encephalopathy.  Hypoxic encephalopathy can occur due to a cardiopulmonary arrest. Despite advanced practices in cardiopulmonary resuscitations, the outcomes after cardiopulmonary arrest seem to be poor and People after successful cardiopulmonary resuscitation often remain with some neurological deficits. LAS is reported very rarely less than 0.5 % in people who survives cardiac arrest. It is commonly confused with myoclonic status epilepticus (MSE) even though examination, imaging, level of disability and time of onset are very different <ref>Wijdicks EFM, Hijdra A, Young GB, Bassetti CL, Wiebe S, Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2006 Jul 25;67(2):203–10 https://pubmed.ncbi.nlm.nih.gov/16864809/</ref>  


  The acute post-hypoxic myoclonus presents within 24 hours of the event is often called myoclonic status epilepticus  (MSE), which is one of the predictors for poor prognosis according to the American Academy of Neurology<sup>(2)</sup>
  The acute post-hypoxic myoclonus presents within 24 hours of the event is often called myoclonic status epilepticus  (MSE), which is one of the predictors for poor prognosis according to the American Academy of Neurology<ref name=":0">Yadavmali T, Lane A. The Lance-Adams Syndrome: Helpful or Just Hopeful, after Cardiopulmonary Arrest. J Intensive Care Soc. 2011 Oct 1;12:324–8 https://www.researchgate.net/publication/285909789_The_Lance-Adams_Syndrome_Helpful_or_Just_Hopeful_after_Cardiopulmonary_Arrest</ref>


The chronic post-hypoxic myoclonus which starts after a few days or weeks in patients who regained consciousness is often stated as LAS, where intentional myoclonus is accompanied when attempting voluntary movements or during a voluntary movement. The myoclonus usually subsides with rest or with relaxation. The severity of the myoclonus is very much related to the precision of the movement. <sup>(2)</sup> The myoclonus gets exaggerated with startle or emotional stress.<sup>(3)</sup>
The chronic post-hypoxic myoclonus which starts after a few days or weeks in patients who regained consciousness is often stated as LAS, where intentional myoclonus is accompanied when attempting voluntary movements or during a voluntary movement. The myoclonus usually subsides with rest or with relaxation. The severity of the myoclonus is very much related to the precision of the movement<ref name=":0" /> The myoclonus gets exaggerated with startle or emotional stress.<ref>The syndrome of intention or action myoclonus as a sequel to hypoxic encephalopathy - PubMed [Internet]. [cited 2023 Jun 4]. Available from: https://pubmed.ncbi.nlm.nih.gov/13928398/</ref>
 
 
=== References ===
<references />

Revision as of 15:48, 4 June 2023

This article or area is currently under construction and may only be partially complete. Please come back soon to see the finished work! (4/06/2023)

Introduction[edit | edit source]

James W Adams and Raymond D Adams described this as a syndrome characterized by intentional myoclonus as a sequel to hypoxic encephalopathy.  Hypoxic encephalopathy can occur due to a cardiopulmonary arrest. Despite advanced practices in cardiopulmonary resuscitations, the outcomes after cardiopulmonary arrest seem to be poor and People after successful cardiopulmonary resuscitation often remain with some neurological deficits. LAS is reported very rarely less than 0.5 % in people who survives cardiac arrest. It is commonly confused with myoclonic status epilepticus (MSE) even though examination, imaging, level of disability and time of onset are very different [1]

  The acute post-hypoxic myoclonus presents within 24 hours of the event is often called myoclonic status epilepticus  (MSE), which is one of the predictors for poor prognosis according to the American Academy of Neurology[2]

The chronic post-hypoxic myoclonus which starts after a few days or weeks in patients who regained consciousness is often stated as LAS, where intentional myoclonus is accompanied when attempting voluntary movements or during a voluntary movement. The myoclonus usually subsides with rest or with relaxation. The severity of the myoclonus is very much related to the precision of the movement[2] The myoclonus gets exaggerated with startle or emotional stress.[3]


References[edit | edit source]

  1. Wijdicks EFM, Hijdra A, Young GB, Bassetti CL, Wiebe S, Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2006 Jul 25;67(2):203–10 https://pubmed.ncbi.nlm.nih.gov/16864809/
  2. 2.0 2.1 Yadavmali T, Lane A. The Lance-Adams Syndrome: Helpful or Just Hopeful, after Cardiopulmonary Arrest. J Intensive Care Soc. 2011 Oct 1;12:324–8 https://www.researchgate.net/publication/285909789_The_Lance-Adams_Syndrome_Helpful_or_Just_Hopeful_after_Cardiopulmonary_Arrest
  3. The syndrome of intention or action myoclonus as a sequel to hypoxic encephalopathy - PubMed [Internet]. [cited 2023 Jun 4]. Available from: https://pubmed.ncbi.nlm.nih.gov/13928398/