Pituitary Gland: Difference between revisions

No edit summary
No edit summary
Line 19: Line 19:
# Prolactin
# Prolactin


Posterior pituitary: neural in origin. Unlike the anterior pituitary, the posterior pituitary is connected directly to the hypothalamus via a nerve tract (hypothalamohypophyseal nerve tract). Oxytocin and antidiuretic hormones are synthesised in the hypothalamus and travel down the nerve tract to be released in the posterior pituitary.<ref>El Sayed SA, Fahmy MW, Schwartz J. [https://www.statpearls.com/articlelibrary/viewarticle/767/ Physiology, pituitary gland.]Available:https://www.statpearls.com/articlelibrary/viewarticle/767/ (accessed 14.1.2023)</ref>  
Posterior pituitary: neural in origin. Unlike the anterior pituitary, the posterior pituitary is connected directly to the hypothalamus via a nerve tract (hypothalamohypophyseal nerve tract). Oxytocin and antidiuretic hormones are synthesised in the hypothalamus and travel down the nerve tract to be released in the posterior pituitary.<ref name=":0">El Sayed SA, Fahmy MW, Schwartz J. [https://www.statpearls.com/articlelibrary/viewarticle/767/ Physiology, pituitary gland.]Available:https://www.statpearls.com/articlelibrary/viewarticle/767/ (accessed 14.1.2023)</ref>  


== Sub Heading 2 ==
== Pathology ==
The most usual problem with the pituitary gland is when a benign tumour, also called an adenoma, develops.
This gland often develops pathology, which may have an effect adjacent intracranial structures or be hormonally active. Pituitary adenomas are present in 14% of autopsy studies and 23% of radiology studies.<ref name=":0" />


Pituitary tumours usually occur in people with no family history of pituitary problems and it is not a hereditary condition.
The more common pituitary conditions include:


Types of tumour
* Hyperprolactinaemia (too much prolactin in the blood).
* [[Growth Hormone|Growth hormone]] deficiency: can delay children’s growth and lead to a child being shorter in height than expected. In adults, the symptoms of growth hormone deficiency include fatigue, weak muscles and bones, excess weight, anxiety, mood problems or sleep problems.
* Hypopituitarism: a deficiency of all the pituitary hormones and causes many different symptoms.


Non-functioning tumour (most cases): tumour doesn’t produce any hormones itself.
Uncommon pituitary conditions include:


Pituitary tumours causing conditions include: acromegaly, Cushing's, diabetes insipidus, hypogonadism, hypopituitarism and prolactinoma.
* Gigantism — where a person grows very tall
* [[Acromegaly]] — where a person’s hands, feet and jaw enlarge
* [[Cushing's Syndrome|Cushing’s syndrome]] — where the body creates too many steroid hormones


== Sub Heading 3 ==
== Sub Heading 3 ==

Revision as of 08:14, 14 January 2023

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton  

Introduction[edit | edit source]

Pituitary-gland-illustration.jpeg

The pituitary gland is a tiny but vital organ and is seen as the master gland, acting as the main endocrine interface between the central nervous system and the entire body. It is found at the base of the brain, below the hypothalamus, in a bony hollow, just behind the bridge of your nose . It is about the size of a pea.[1][2] The hypothalamus controls the pituitary by sending it messages.[3]

Blood vessels and neural tract

Anterior and Posterior Pituitary

Anterior pituitary: the largest part of the gland, secreting six hormones, each with a specific functions and target organs:

  1. Growth hormone (somatotropin)
  2. Thyroid stimulating hormone (TSH)
  3. Adrenocorticotropic hormone (ACTH)
  4. Follicular stimulating hormone (FSH)
  5. Luteinizing hormone (LH)
  6. Prolactin

Posterior pituitary: neural in origin. Unlike the anterior pituitary, the posterior pituitary is connected directly to the hypothalamus via a nerve tract (hypothalamohypophyseal nerve tract). Oxytocin and antidiuretic hormones are synthesised in the hypothalamus and travel down the nerve tract to be released in the posterior pituitary.[4]

Pathology[edit | edit source]

This gland often develops pathology, which may have an effect adjacent intracranial structures or be hormonally active. Pituitary adenomas are present in 14% of autopsy studies and 23% of radiology studies.[4]

The more common pituitary conditions include:

  • Hyperprolactinaemia (too much prolactin in the blood).
  • Growth hormone deficiency: can delay children’s growth and lead to a child being shorter in height than expected. In adults, the symptoms of growth hormone deficiency include fatigue, weak muscles and bones, excess weight, anxiety, mood problems or sleep problems.
  • Hypopituitarism: a deficiency of all the pituitary hormones and causes many different symptoms.

Uncommon pituitary conditions include:

  • Gigantism — where a person grows very tall
  • Acromegaly — where a person’s hands, feet and jaw enlarge
  • Cushing’s syndrome — where the body creates too many steroid hormones

Sub Heading 3[edit | edit source]

Resources[edit | edit source]

  • bulleted list
  • x

or

  1. numbered list
  2. x

References[edit | edit source]

  1. Banas A, Banas K, Furgal-Borzych A, Kwiatek WM, Pawlicki B, Breese MB. The pituitary gland under infrared light–in search of a representative spectrum for homogeneous regions. Analyst. 2015;140(7):2156-63. Available:https://pubmed.ncbi.nlm.nih.gov/25574521/ (accessed 14.1.2023)
  2. Radiopedia Pituitary Gland Available:https://radiopaedia.org/articles/pituitary-gland (accessed 14.1.2023)
  3. The pituitary foundation What is the pituitary gland? Available:https://www.pituitary.org.uk/information/what-is-the-pituitary-gland/ (accessed 14.1.2023)
  4. 4.0 4.1 El Sayed SA, Fahmy MW, Schwartz J. Physiology, pituitary gland.Available:https://www.statpearls.com/articlelibrary/viewarticle/767/ (accessed 14.1.2023)