Ehlers-Danlos Syndrome: Difference between revisions

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== Associated Co-morbidities ==
== Associated Co-morbidities ==


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Many different medical conditions/disease states occur in individuals with EDS.&nbsp; Examples of co-morbidities include:
 
*Gastroesophageal reflux
*Gastritis
*Irritable Bowel Sydrome
*Autonomic Dysfunction (neurally mediated hypotension, postural orthostatic tachycardia syndrome, paroxysmal supraventricular tachycardia)
*Aortic root dilatation
*Mitral valve prolapse


== Medications  ==
== Medications  ==

Revision as of 23:25, 17 February 2010

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.

Lead Editors - Your name will be added here if you are a lead editor on this page.  Read more.

Definition/Description[edit | edit source]

Ehlers-Danlos syndrome is a hereditary collagen disorder characterized by articular hypermobility, dermal hyperelasticity, and widespread tissue fragility (The Merck Manual).

Prevalence[edit | edit source]

Combined prevalence of all subtypes of EDS is about 1 per 5,000.  Hypermobility and classic subtypes are the most common with prevalencs of 1 per 10,000-15,000 and 1 per 20,000-40,000 respectively.  EDS demonstrates equal prevalence amongst males and females of all racial and ethnic backgrounds (Ehlers Danlos National Foundation, Steiner RD - emedicine, Levy HP - Gene Reviews, U.S. National Library of Medicine).

Characteristics/Clinical Presentation[edit | edit source]

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Associated Co-morbidities[edit | edit source]

Many different medical conditions/disease states occur in individuals with EDS.  Examples of co-morbidities include:

  • Gastroesophageal reflux
  • Gastritis
  • Irritable Bowel Sydrome
  • Autonomic Dysfunction (neurally mediated hypotension, postural orthostatic tachycardia syndrome, paroxysmal supraventricular tachycardia)
  • Aortic root dilatation
  • Mitral valve prolapse

Medications[edit | edit source]

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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

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Causes[edit | edit source]

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Systemic Involvement[edit | edit source]

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Medical Management (current best evidence)[edit | edit source]

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Physical Therapy Management (current best evidence)[edit | edit source]

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Alternative/Holistic Management (current best evidence)[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Case Reports[edit | edit source]

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Resources
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Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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