Crohn's Disease: Difference between revisions
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== Definition/Description == | == Definition/Description == | ||
Crohn’s disease is a form of inflammatory bowel disease (IBD) that causes inflammation to the lining of the digestive or gastrointestinal (GI) tract <ref name="NDDIC">National Digestive Diseases Information Clearinghouse (NDDIC). Crohn’s disease. http://digestive.niddk.nih.gov/ddiseases/pubs/crohns/ (accessed 4 March 2010).</ref> and may be a result of an immune system malfunction. The immune system sees the bacteria and organisms that lie within the GI tract and intestines and mistakes them for outside invaders to the body. In response to this, the body produces extra white blood cells to the GI tract to fight off the invaders, which creates inflammation within the lining of the tract. Chronic inflammation may result in ulcerations within the layers of the tract <ref name="Living with Crohn's">Living with Crohn’s Disease. Inside Crohn’s disease. https://www.livingwithcrohnsdisease.com/livingwithcrohnsdisease/crohns_disease/inside_crohns.html (accessed 4 March 2010)</ref>. The inflammation can occur to any portion of the GI tract, from mouth to anus and can affect all layers of the intestinal tract while healthy bowel layers may be interspaced between the diseased portions of the bowel. The most commonly affected portion of GI tract affected is the lower portion of the small intestine, or ileum <ref name="NDDIC" />. Due to the inflammation, abdominal pain, diarrhea and malnutrition can be a result <ref name="mayo">MayoClinic. Crohn’s Disease. http://mayoclinic.com/health/crohns-disease/DS00104/DSECTION=causes (accessed 4 March 2010)</ref>. Crohn’s disease is also referred to as granulomatous enteritis or colitis, ileitis, regional enteritis, or terminal ileitis. This disease is similar in some aspects to ulcerative colitis, but the difference lies in the fact that ulcerative colitis produces inflammation only within the colon or rectum while Crohn’s disease produces inflammation within the colon, rectum, small intestine, stomach, mouth and esophagus. The inflammation caused by Crohn’s disease has the potential to affect the deeper layers more than ulcerative colitis <ref name="MedicineNet">MedicineNet. Crohn’s Disease. http://www.medicinenet.com/crohns_disease/page2.htm (accessed 4 March 2010)</ref>. While these two conditions are very similar, approximately 10 percent of individuals are unable to pinpoint whether the disease process is ulcerative colitis or Crohn’s disease. For these individuals, they are then diagnosed with indeterminate colitis <ref name="CCFA">Crohn’s and Colitis Foundation of America (CCFA). About Crohn’s Disease. http://ccfa.org/info/about/crohns (accessed 4 March 2010)</ref>.<br> | Crohn’s disease is a form of inflammatory bowel disease (IBD) that causes inflammation to the lining of the digestive or gastrointestinal (GI) tract <ref name="NDDIC">National Digestive Diseases Information Clearinghouse (NDDIC). Crohn’s disease. http://digestive.niddk.nih.gov/ddiseases/pubs/crohns/ (accessed 4 March 2010).</ref> and may be a result of an immune system malfunction. The immune system sees the bacteria and organisms that lie within the GI tract and intestines and mistakes them for outside invaders to the body. In response to this, the body produces extra white blood cells to the GI tract to fight off the invaders, which creates inflammation within the lining of the tract. Chronic inflammation may result in ulcerations within the layers of the tract <ref name="Living with Crohn's">Living with Crohn’s Disease. Inside Crohn’s disease. https://www.livingwithcrohnsdisease.com/livingwithcrohnsdisease/crohns_disease/inside_crohns.html (accessed 4 March 2010)</ref>. The inflammation can occur to any portion of the GI tract, from mouth to anus and can affect all layers of the intestinal tract while healthy bowel layers may be interspaced between the diseased portions of the bowel. | ||
The most commonly affected portion of GI tract affected is the lower portion of the small intestine, or ileum <ref name="NDDIC" />. Due to the inflammation, abdominal pain, diarrhea and malnutrition can be a result <ref name="mayo">MayoClinic. Crohn’s Disease. http://mayoclinic.com/health/crohns-disease/DS00104/DSECTION=causes (accessed 4 March 2010)</ref>. Crohn’s disease is also referred to as granulomatous enteritis or colitis, ileitis, regional enteritis, or terminal ileitis. This disease is similar in some aspects to ulcerative colitis, but the difference lies in the fact that ulcerative colitis produces inflammation only within the colon or rectum while Crohn’s disease produces inflammation within the colon, rectum, small intestine, stomach, mouth and esophagus. The inflammation caused by Crohn’s disease has the potential to affect the deeper layers more than ulcerative colitis <ref name="MedicineNet">MedicineNet. Crohn’s Disease. http://www.medicinenet.com/crohns_disease/page2.htm (accessed 4 March 2010)</ref>. While these two conditions are very similar, approximately 10 percent of individuals are unable to pinpoint whether the disease process is ulcerative colitis or Crohn’s disease. For these individuals, they are then diagnosed with indeterminate colitis <ref name="CCFA">Crohn’s and Colitis Foundation of America (CCFA). About Crohn’s Disease. http://ccfa.org/info/about/crohns (accessed 4 March 2010)</ref>.<br> | |||
== Prevalence == | == Prevalence == |
Revision as of 00:24, 6 March 2010
Original Editors - Sarah Bailey Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
Crohn’s disease is a form of inflammatory bowel disease (IBD) that causes inflammation to the lining of the digestive or gastrointestinal (GI) tract [1] and may be a result of an immune system malfunction. The immune system sees the bacteria and organisms that lie within the GI tract and intestines and mistakes them for outside invaders to the body. In response to this, the body produces extra white blood cells to the GI tract to fight off the invaders, which creates inflammation within the lining of the tract. Chronic inflammation may result in ulcerations within the layers of the tract [2]. The inflammation can occur to any portion of the GI tract, from mouth to anus and can affect all layers of the intestinal tract while healthy bowel layers may be interspaced between the diseased portions of the bowel.
The most commonly affected portion of GI tract affected is the lower portion of the small intestine, or ileum [1]. Due to the inflammation, abdominal pain, diarrhea and malnutrition can be a result [3]. Crohn’s disease is also referred to as granulomatous enteritis or colitis, ileitis, regional enteritis, or terminal ileitis. This disease is similar in some aspects to ulcerative colitis, but the difference lies in the fact that ulcerative colitis produces inflammation only within the colon or rectum while Crohn’s disease produces inflammation within the colon, rectum, small intestine, stomach, mouth and esophagus. The inflammation caused by Crohn’s disease has the potential to affect the deeper layers more than ulcerative colitis [4]. While these two conditions are very similar, approximately 10 percent of individuals are unable to pinpoint whether the disease process is ulcerative colitis or Crohn’s disease. For these individuals, they are then diagnosed with indeterminate colitis [5].
Prevalence[edit | edit source]
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- ↑ 1.0 1.1 National Digestive Diseases Information Clearinghouse (NDDIC). Crohn’s disease. http://digestive.niddk.nih.gov/ddiseases/pubs/crohns/ (accessed 4 March 2010).
- ↑ Living with Crohn’s Disease. Inside Crohn’s disease. https://www.livingwithcrohnsdisease.com/livingwithcrohnsdisease/crohns_disease/inside_crohns.html (accessed 4 March 2010)
- ↑ MayoClinic. Crohn’s Disease. http://mayoclinic.com/health/crohns-disease/DS00104/DSECTION=causes (accessed 4 March 2010)
- ↑ MedicineNet. Crohn’s Disease. http://www.medicinenet.com/crohns_disease/page2.htm (accessed 4 March 2010)
- ↑ Crohn’s and Colitis Foundation of America (CCFA). About Crohn’s Disease. http://ccfa.org/info/about/crohns (accessed 4 March 2010)