Paget's Disease: Difference between revisions
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== Definition/Description == | == Definition/Description == | ||
Also known as Osteitis Deformans, Paget's disease of the bone is a metabolic bone disease caused by increased bone resorption followed by excessive unrestricted bone formation, due to activated osteoclasts. The normal bone marrow is replaced by increased and unorganized collagen and fibrous tissue, which lacks the structural stability of normal bone. This increased bone mass formation leads to complications such as fractures, arthritis, deformities, and pain due to its weakened condition. | |||
== Prevalence == | == Prevalence == |
Revision as of 18:51, 21 February 2010
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Definition/Description[edit | edit source]
Also known as Osteitis Deformans, Paget's disease of the bone is a metabolic bone disease caused by increased bone resorption followed by excessive unrestricted bone formation, due to activated osteoclasts. The normal bone marrow is replaced by increased and unorganized collagen and fibrous tissue, which lacks the structural stability of normal bone. This increased bone mass formation leads to complications such as fractures, arthritis, deformities, and pain due to its weakened condition.
Prevalence[edit | edit source]
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Characteristics/Clinical Presentation[edit | edit source]
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