Radiation Side Effects and Syndromes: Difference between revisions

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== Prevalence  ==
== Prevalence  ==


Nearly two-thirds of all cancer patients will recieve radiation therapy.<sup>1</sup>
Nearly two-thirds of all cancer patients will recieve radiation therapy.<sup>2</sup>


== Characteristics/Clinical Presentation  ==
== Characteristics/Clinical Presentation  ==

Revision as of 23:43, 7 April 2013

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Original Editors -Alicia Dupilka & Kristin Gramling from Bellarmine University's Pathophysiology of Complex Patient Problems project.

Lead Editors - Your name will be added here if you are a lead editor on this page.  Read more.

Definition/Description[edit | edit source]

Radiation therapy is when radiation is delivered to a specific area of the body to try and treat a disease, usually cancer.  The goal of the radiation is to kill rapidly dividing cancer cells while sparing slower dividing somatic cells.1 Radiation is usually used in conjuction with surgery or chemotherapy. 

Prevalence[edit | edit source]

Nearly two-thirds of all cancer patients will recieve radiation therapy.2

Characteristics/Clinical Presentation[edit | edit source]

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Associated Co-morbidities[edit | edit source]

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Medications[edit | edit source]

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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

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Etiology/Causes[edit | edit source]

Risk Factors:

Dependent on organ radiated, individual tolerance, tumor type, volume radiated and fraction size/dosage.

Neurotoxicity

- High total dose and fractionation dose

- Large volume radiated

- Increased edema

- Age <12 or >60 years

- Concurrent chemotherapy

- Underlying diseases affecting the vascular structures (Diabetes, HTN)

- Stereotactic radiation surgery and brachytherapy (internal radiation)

Dermatitis

- Total dose/volume and fractionation dose

- Surface area exposed

Acute Enterocolitis

- Large volume

- High total dose and fractionation dose

- Concurrent chemotherapy

Chronic Entercolitis

- Older age

- Postoperative radiation

- Presence of collagen vascular disease

- Concurrent chemotherapy

- Poor radiation technique

Pulmonary

- Older age

- Lower performance status

- Lower pulmonary baseline function

- Large volume treated

Systemic Involvement[edit | edit source]

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Medical Management (current best evidence)[edit | edit source]

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Physical Therapy Management (current best evidence)[edit | edit source]

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Alternative/Holistic Management (current best evidence)[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Case Reports/ Case Studies[edit | edit source]

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Resources
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Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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