Kaposi Sarcoma: Difference between revisions
(Created page with "{{subst: Under Construction}} {{subst: Condition}}") |
No edit summary |
||
| Line 3: | Line 3: | ||
</div> | </div> | ||
<div class="editorbox"> '''Original Editor '''- [[User: | <div class="editorbox"> '''Original Editor '''- [[User:Carina Therese Magtibay|Carina Therese Magtibay]]<br> | ||
'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}}</div> | '''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}}</div> | ||
== | == Introduction == | ||
Kaposi sarcoma (KS) is a soft tissue tumor that affects immunocompromised people including organ transplant recipients and people with [[Human Immunodeficiency Virus (HIV)|acquired immunodeficiency syndrome]] (AIDs).<ref name=":0">Bishop BN, Lynch DT. [https://www.ncbi.nlm.nih.gov/books/NBK534839/#article-23842.s3 Kaposi sarcoma.] InStatPearls [Internet] 2022 Jun 11. StatPearls Publishing.</ref><ref name=":1">Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. [https://www.nature.com/articles/s41572-019-0060-9 Kaposi sarcoma]. Nature reviews Disease primers. 2019 Jan 31;5(1):9.</ref> | |||
Moritz Kaposi, an Austro-Hungarian dermatologist, first published "Idiopathisches multiples Pigmentsarkom der Haut" in 1872. He reported several cases of a multifocal pigmented sarcoma of the skin in elderly European men, all of whom died within a span of two years.<ref name=":1" /><ref>Kaposi. Idiopathisches multiples pigmentsarkom der haut. Archiv für Dermatologie und Syphilis. 1872 Jun;4:265-73.</ref><br> | |||
== Mechanism of Injury / Pathological Process | == Mechanism of Injury / Pathological Process == | ||
Human herpesvirus/Kaposi sarcoma herpesvirus (HHV-8) was discovered as a causative agent of Kaposi sarcoma as the AIDS epidemic progressed in the 1980s.<ref name=":0" /> | |||
HHV-8 interferes with many normal cell functions and requires cofactors like cytokines or specific proteins to result in the development of Kaposi sarcoma.<ref>Mariggiò G, Koch S, Schulz TF. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597742/ Kaposi sarcoma herpesvirus pathogenesis]. Philosophical Transactions of the Royal Society B: Biological Sciences. 2017 Oct 19;372(1732):20160275.</ref> | |||
== Clinical Presentation == | == Clinical Presentation == | ||
Revision as of 09:40, 30 November 2023
This article or area is currently under construction and may only be partially complete. Please come back soon to see the finished work! (30/11/2023)
Top Contributors - Carina Therese Magtibay and Ines Musabyemariya
Introduction[edit | edit source]
Kaposi sarcoma (KS) is a soft tissue tumor that affects immunocompromised people including organ transplant recipients and people with acquired immunodeficiency syndrome (AIDs).[1][2]
Moritz Kaposi, an Austro-Hungarian dermatologist, first published "Idiopathisches multiples Pigmentsarkom der Haut" in 1872. He reported several cases of a multifocal pigmented sarcoma of the skin in elderly European men, all of whom died within a span of two years.[2][3]
Mechanism of Injury / Pathological Process[edit | edit source]
Human herpesvirus/Kaposi sarcoma herpesvirus (HHV-8) was discovered as a causative agent of Kaposi sarcoma as the AIDS epidemic progressed in the 1980s.[1]
HHV-8 interferes with many normal cell functions and requires cofactors like cytokines or specific proteins to result in the development of Kaposi sarcoma.[4]
Clinical Presentation[edit | edit source]
add text here relating to the clinical presentation of the condition
Diagnostic Procedures[edit | edit source]
add text here relating to diagnostic tests for the condition
Outcome Measures[edit | edit source]
add links to outcome measures here (see Outcome Measures Database)
Management / Interventions
[edit | edit source]
add text here relating to management approaches to the condition
Differential Diagnosis
[edit | edit source]
add text here relating to the differential diagnosis of this condition
Resources
[edit | edit source]
add appropriate resources here
References[edit | edit source]
- ↑ 1.0 1.1 Bishop BN, Lynch DT. Kaposi sarcoma. InStatPearls [Internet] 2022 Jun 11. StatPearls Publishing.
- ↑ 2.0 2.1 Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. Kaposi sarcoma. Nature reviews Disease primers. 2019 Jan 31;5(1):9.
- ↑ Kaposi. Idiopathisches multiples pigmentsarkom der haut. Archiv für Dermatologie und Syphilis. 1872 Jun;4:265-73.
- ↑ Mariggiò G, Koch S, Schulz TF. Kaposi sarcoma herpesvirus pathogenesis. Philosophical Transactions of the Royal Society B: Biological Sciences. 2017 Oct 19;372(1732):20160275.
