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== Introduction ==
== Introduction ==
[[File:Tracheobronchial tree.jpeg|thumb|The lower respiratory tract <small>1: Trachea</small>
<small>2: Mainstem bronchus</small>
<small>3: Lobar bronchus</small>
<small>4: Segmental bronchus</small>
<small>5: Bronchiole,</small>
<small>6:</small> <small>Alveolar duct ,</small>
<small>7:Alveolus</small> <ref>https://en.wikipedia.org/wiki/Respiratory_tract </ref>|alt=|300x300px]]
The tracheobronchial tree is a branching tree of airways composed of:
The tracheobronchial tree is a branching tree of airways composed of:


* the trachea
# the trachea
* the bronchi
# the bronchi
* the bronchioles.<ref name=":0">[https://www.ncbi.nlm.nih.gov/books/NBK556044/ Downey] RP, Samra NS. [https://www.ncbi.nlm.nih.gov/books/NBK556044/ Anatomy, Thorax, Tracheobronchial Tree]. InStatPearls [Internet] 2020 Jul 31. StatPearls Publishing.</ref>
# the bronchioles.<ref name=":0">[https://www.ncbi.nlm.nih.gov/books/NBK556044/ Downey] RP, Samra NS. [https://www.ncbi.nlm.nih.gov/books/NBK556044/ Anatomy, Thorax, Tracheobronchial Tree]. InStatPearls [Internet] 2020 Jul 31. StatPearls Publishing.</ref>
Its main function is the transfer of air from the environment to the lungs for gas exchange.


The tracheobronchial tree has a branching structure of approximately 23 branches or generations extending from the trachea (generation 0) to the last order of terminal bronchioles (generation 23).<ref>Gauthier SP, Wolfson MR, Deoras KS, Shaffer TH. [https://www.nature.com/articles/pr199230.pdf?origin=ppub Structure-function of airway generations 0 to 4 in the preterm lamb.] Pediatric research. 1992 Feb;31(2):157-62.</ref><ref>Patwa A, Shah A. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613399/#:~:text=The%20terminal%20bronchioles%20(generation%2016,are%20completely%20lined%20with%20alveoli. Anatomy and physiology of respiratory system relevant to anaesthesia. Indian journal of anaesthesia]. 2015 Sep;59(9):533.</ref>  
[[File:Lower respiratory truck.jpeg|center|frame|''.                              Figure 1: Lower respiratory tract'']]
 
Its main function is the transfer of air from the environment to the [[Lung Anatomy|lungs]] for gas exchange.
<u>Conducting zones</u> : 
The tracheobronchial tree has a branching structure of approximately 23 branches or generations extending from the trachea <small>(generation 0)</small> to the last order of terminal bronchioles <small>(generation 23)</small>.<ref>Gauthier SP, Wolfson MR, Deoras KS, Shaffer TH. [https://www.nature.com/articles/pr199230.pdf?origin=ppub Structure-function of airway generations 0 to 4 in the preterm lamb.] Pediatric research. 1992 Feb;31(2):157-62.</ref><ref>Patwa A, Shah A. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613399/#:~:text=The%20terminal%20bronchioles%20(generation%2016,are%20completely%20lined%20with%20alveoli. Anatomy and physiology of respiratory system relevant to anaesthesia. Indian journal of anaesthesia]. 2015 Sep;59(9):533.</ref>
{| class="wikitable"
!'''Generations'''
!
|-
|''Conducting zones''
|
|-
|0
|<small>Trachea</small>
|-
|1
|<small>Primary bronchus</small>
|-
|2
|<small>Lobar bronchus</small>
|-
|3<sup>rd</sup>
|<small>Segmental bronchus</small>
|-
|4, 5, 6
|<small>Subsegmental bronchus</small>
|-
|16
|<small>Terminal bronchioles</small>
|-
|''Respiratory zones''
|
|-
|17- 19
|<small>Respiratory bronchioles</small>
|-
|20-23
|<small>Alveolar ducts , alveoli</small>
|}
== Trachea ==
== Trachea ==
[[File:Anatomy of trachea.png|thumb|321x321px|alt=|border]]The main functions of the trachea comprise air flow into the lungs, mucociliary clearance. The trachea is a C-shaped  structure, flexible tube  that is composed of '''hyaline cartilage on the anterior and lateral walls.''' Also contains of the trachealis smooth muscle forming the posterior wall of the trachea .Also the trachea is composed of several primary structural annular ligament.<ref name=":1">Mieczkowski B, Seavey BF. [https://www.ncbi.nlm.nih.gov/books/NBK448070/ Anatomy, Head and Neck, Trachea.]</ref>  Posterior surface of  the trachea is flat where its cartilaginous rings are incomplete (anatomy book )
The main functions of the trachea is to allow the passage of air into the lungs and provide a vital role in the mucociliary clearance of the respiratory system. [[File:Anatomy of trachea.png|thumb|350x350px|alt=|border|                                                              <small>''Figure 2:  Anatomy of the trachea''</small> |left]]
 
===== Characteristics of the trachea =====
# The trachea descends from the larynx into the lung.<ref name=":0" />
* The [[Trachea and Larynx|trachea]] descends from the larynx into the lung.<ref name=":0" />
# The trachea is tube 10-12 cm.
* The trachea is tube 12 cm.<ref>Brand-Saberi BE, Schäfer T. [https://pubmed.ncbi.nlm.nih.gov/24295654/ Trachea: anatomy and physiology. Thoracic surgery clinics]. 2014 Feb 1;24(1):1-5.</ref>
# Is situated anterior to the oesophagus. (biblio)
* Is situated anterior to the oesophagus.
# .Extends from cricoid cartilage (c6 level) by cricothyroid membrane  to carina (level of sternal angle ). At the level of carina the trachea bifurcates into the right and left m<nowiki/>ain bronchi.<ref name=":0" /><ref name=":1" />
* .Extends from cricoid cartilage (c6 level) by cricothyroid membrane  to carina (level of sternal angle).
<code>Inner mucosal layer made of ciliated pseudostratified columnar epithelium with goblet cells. Goblet cells produce mucus that traps airborne particles and microorganisms, and the cilia propel the mucus upward, where it is either swallowed or expelled.</code>
* At the level of sternal angle, the trachea bifurcates into the right<nowiki/> and left main bronchi.<ref name=":0" /><ref name=":1" />
The trachea is a C-shaped  structure, flexible tube  that is composed of hyaline cartilage on the anterior and lateral walls. The posterior wall of the [[Trachea and Larynx|trachea]] is formed by the trachealis smooth muscle .Also the trachea is composed of several primary structural annular ligaments.<ref name=":1">Mieczkowski B, Seavey BF. [https://www.ncbi.nlm.nih.gov/books/NBK448070/ Anatomy, Head and Neck, Trachea.]</ref> <ref name=":2">Clinically Oriented Anatomy, Keith L. Moore, Arthur F. Dalley, Anne M. R. Agur, Philadelphia, United States</ref>


===== '''Hyaline cartilage''' =====
===== '''Hyaline cartilage''' =====
# Series of 16 to 20 hyaline cartilage rings one top the other  each is individually connected by an annular ligament.
# Series of 16 to 20 hyaline cartilage rings connected by an annular ligament.
# The tracheal cartilaginous rings, are responsible for keeping the trachea lumen open in spite of the changes in intrathoracic pressure that occur during respiration, and hence prevent air flow limitation.
# The tracheal cartilaginous rings, are responsible for keeping the trachea lumen open in spite of the changes in intrathoracic pressure that occur during respiration.<ref name=":1" />


===== '''Trachealis muscle''' =====
===== '''Trachealis muscle''' =====
* Type of muscle = Smooth muscle  
* Type of muscle : Smooth muscle
* Connects the ends of the C-shaped tracheal cartilages.
* Connects the ends of the C-shaped tracheal cartilages.
* Is in contact with the anterior esophagus[[File:Cross section trachea.png|thumb|400x400px|alt=]]The trachealis muscle functions to constrict the airway by pulling the cartilages together, decrease the diameter , allowing for increased expiratory force during coughing with the smaller aperture allowing greater velocity to be achieved and the particle to be expelled. http://education.med.nyu.edu/Histology/courseware/modules/respiratory-sy/respiratory.07.html. This action is helpful, especially when eating food, which requires the expansion of the esophagus.
 
* Is in contact with the anterior esophagus
 
* The trachealis muscle functions to constrict the airway by pulling the cartilages together. By decreasing the diameter of  the airway, it allows for increased expiratory force during coughing and thus allows greater velocity to be achieved for the particle to be expelled. This action is helpful, especially when eating food, which requires the expansion of the esophagus.<ref name=":0" />
[[File:Cross section trachea.png|thumb|700x700px|alt=|                                                                                                                                                                                                                                                                                                                                ''<small>Figure 3: Cross-section of a trachea</small>'' |center]]


==== Bronchi ====
==== Bronchi ====
At the level of the fifth thoracic vertebra, the trachea divides into the left and right main bronchi. The right main bronchus has a length of 2.5 cm, and the left main bronchus is 5 cm long. [https://www.sciencedirect.com/topics/medicine-and-dentistry/trachealis-muscle https://www.sciencedirect.com/topics/medicine-and-dentistry/trachealis-]
At the level of the fifth [[Thoracic Anatomy|thoracic vertebra]], the trachea divides into the left and right main bronchi. The right main bronchus has a length of 2.5 cm, and the left main bronchus is 5 cm long.
 
The trachea divides at the carina (at the level of the sternal angle) to give rise to the two primary bronchi – '''the right and left bronchus''' (figure X). Differences between right and left bronchus are illustrated below in table X .The right and left bronchus conduct air from the trachea into the right and left lung respectively.


The '''primary bronchi''' then branch into s'''econdary bronchi (lobar bronchi)''' – three on the right and two on the left. Each secondary bronchus supplies a lobe of the lung.
The trachea divides at the carina (at the level of the sternal angle) to give rise to the two primary bronchi – '''the right and left bronchus''' (figure 4). Differences between right and left bronchus are illustrated below in table 1 .The right and left bronchus conduct air from the trachea into the right and left lung respectively.[[File:Tracheobronchial tree.jpeg|thumb|<small>Figure 4: The lower respiratory tract</small> <small>''1:Trachea,''</small> ''<small>2: Mainstem bronchus</small>'' <small>''3: Lobar bronchus,''</small><small>''4: Segmental bronchus''</small><small>'',''</small> <small>''5: Bronchiole''</small><small>'',''</small>''<small>6:</small> <small>Alveolar duct,</small>'' <small>''7:Alveolus''</small> |alt=|300x300px|center]]The '''primary bronchi''' then branch into s'''econdary bronchi (lobar bronchi)''' – three on the right and two on the left. Each secondary bronchus supplies a lobe of each lung.


Each secondary bronchi (lobar bronchi) subsequently divide into narrower '''tertiary bronchi (segmental bronchi)''' that supply bronchopulmonary segments (largest subdivisions of a lobe).
Each secondary bronchi (lobar bronchi) subsequently divide into narrower '''tertiary bronchi (segmental bronchi)''' that supply bronchopulmonary segments (largest subdivisions of a lobe).


'''Segmental bronchi'''  undergo further branching to form numerous smaller airways, called the '''bronchioles,''' .
'''Segmental bronchi'''  undergo further branching to form numerous smaller airways, called the '''bronchioles'''.<ref name=":2" /><ref>Eleanor Main & Linda Denehy, Cardiorespiratory Physiotherapy: Adults and paediatrics, 5th Edition</ref>


{| class="wikitable sortable mw-collapsible mw-collapsed"
{| class="wikitable"
|'''Right Bronchus'''
|'''Right Bronchus'''        
|'''Left Bronchus'''
|
# Wider
#  More vertical
# Shorter (2.5 cm)
# Supported by C shaped cartilages
# 20 to 30 degree angle
|-
|-
|<nowiki>-       Wider</nowiki>
|'''Left Bronchus'''      
 
|
-       More vertical
# Narrower
 
# More angular
-       Shorter (2-3cm)
# Longer (5cm)
# Supported by C shaped cartilages
# 40 to 60 degree angle


-       Supported by C shaped cartilages
-       20 to 30 degree angle
|<nowiki>-       Narrower</nowiki>
-       More angular
-       Longer (5cm)
-       Supported by C shaped cartilages
-       40 to 60 degree angle
|}
|}
Table 1<ref name=":2" />


=== Bronchioles  ===
=== Bronchioles  ===
[[File:Healthy alveoli Primal.png|thumb]]
Bronchioles arise from segmental bronchi and represent the smaller branches of the bronchial tree. They differ histologically from bronchi as they lack C shaped cartilages in their walls.<ref>Amador C, Weber C, Varacallo M. [https://www.ncbi.nlm.nih.gov/books/NBK537353/ Anatomy, thorax, bronchial.] InStatPearls [Internet] 2021 Aug 11. StatPearls Publishing.
Bronchioles arise from segmental bronchi and represent the smaller branches of the bronchial tree. They differ histologically from bronchi as they lack C shaped cartilages in their walls.
 
BibTeXEndNoteRefManRefWorks</ref>


Bronchioles initially divide into many generations of '''conducting bronchioles''' which eventually divide further into '''terminal bronchioles''' which further divide into r'''espiratory bronchioles'''.
Bronchioles initially divide into many generations of '''conducting bronchioles''' which eventually divide further into '''terminal bronchioles''' which further divide into r'''espiratory bronchioles'''.


* '''Conducting bronchioles ( part of conducting zone)'''
'''Conducting bronchioles (part of conducting zone)'''
** segmental bronchi give rise to 20 to 25 generations of conducting bronchioles that further divide to terminal bronchioles.
* Segmental bronchi give rise to 20 to 25 generations of conducting bronchioles that further divide to terminal bronchioles.
** function - as part of the conducting system they allow air to travel from the trachea to alveoli where gas exchange occurs.
* Function - as part of the conducting system they allow air to travel from the trachea to alveoli where gas exchange occurs.
* '''Terminal bronchioles (part of conducting zone)'''
** represent the last part of the conducting part of the bronchial tree and give rise to several generations of respiratory bronchiole
** function - as part of the conducting system they allow air to travel from the trachea to alveoli where gas exchange occurs.
* '''Respiratory bronchioles ( part of respiratory zone)'''
** distinguishable to other types of bronchioles by the presence of alveoli) extending from their lumens
** function - represent the first part of the respiratory airways where they facilitate gas exchange
 
This exchange occurs in the respiratory bronchioles, alveolar ducts and alveoli, which collectively form the respiratory zones deep in the lungs.
 
{| class="wikitable"
|+
!'''Generations'''
!
|-
|''Conducting zones''
|
|-
|0
|<small>Trachea</small>
|-
|1
|<small>Primary bronchus</small>
|-
|2
|<small>Lobar bronchus</small>
|-
|3<sup>rd</sup>
|<small>Segmental bronchus</small>
|-
|4, 5, 6
|<small>Subsegmental bronchus</small>
|-
|16
|<small>Terminal bronchioles</small>
|-
|''Respiratory zones''
|
|-
|17- 19
|<small>Respiratory bronchioles</small>
|-
|20-23
|<small>Alveolar ducts , alveoli</small>
|}


'''Terminal bronchioles (part of conducting zone)'''
* Represent the last part of the conducting part of the bronchial tree and give rise to several generations of respiratory bronchioles
* Function - as part of the conducting system they allow air to travel from the trachea to alveoli where gas exchange occurs.<ref name=":2" />


'''Respiratory bronchioles ( part of respiratory zone)'''
* Distinguishable to other types of bronchioles by the presence of alveoli extending from their lumens
* Function - represent the first part of the respiratory airways where they facilitate gas exchange<ref name=":2" />


Resources
Gas exchange occurs in the respiratory bronchioles, alveolar ducts and alveoli, which collectively form the respiratory zones deep in the lungs.{{#ev:youtube|5F8XdE1d0xk|500}}<ref>Meditay.Trachea, Bronchial Tree and Alveolar Tree (Parts, Structures and Walls) - Anatomy Available from:https://www.youtube.com/watch?v=5F8XdE1d0xk</ref>
*bulleted list
*x
or


#numbered list
== Clinical relevance ==
#x


Physiotherapy plays an important role in most respiratory conditions like asthma , COPD,  cystic fibrosis and others. A group of techniques such as active cycles of breathing, huffing, [[Autogenic Drainage|autogenic drainage]], coughing, and forced expiratory can be used by physiotherapists to help remove extra mucus from tracheobronchial secretions. Thick or excessive secretions produced by respiratory disorders may become accumulated and as a result may develop bronchial infections. The role of physiotherapy is minimising the symptoms and educating people who have respiratory diseases on how to self manage their symptoms and prevent further complications.
== References  ==
== References  ==


<references />
<references />
[[Category:Anatomy]]
{{DEFAULTSORT:Tracheobronchial tree}}
[[Category:Cardiopulmonary]]
[[Category:Anatomy Project]]
[[Category:Anatomical Landmarks]]

Latest revision as of 17:43, 19 July 2022

Original Editor - Stella Constantinides

Top Contributors - Stella Constantinides and Kim Jackson  

Introduction[edit | edit source]

The tracheobronchial tree is a branching tree of airways composed of:

  1. the trachea
  2. the bronchi
  3. the bronchioles.[1]
. Figure 1: Lower respiratory tract

Its main function is the transfer of air from the environment to the lungs for gas exchange. The tracheobronchial tree has a branching structure of approximately 23 branches or generations extending from the trachea (generation 0) to the last order of terminal bronchioles (generation 23).[2][3]

Trachea[edit | edit source]

The main functions of the trachea is to allow the passage of air into the lungs and provide a vital role in the mucociliary clearance of the respiratory system.

Figure 2: Anatomy of the trachea
Characteristics of the trachea[edit | edit source]
  • The trachea descends from the larynx into the lung.[1]
  • The trachea is tube 12 cm.[4]
  • Is situated anterior to the oesophagus.
  • .Extends from cricoid cartilage (c6 level) by cricothyroid membrane  to carina (level of sternal angle).
  • At the level of sternal angle, the trachea bifurcates into the right and left main bronchi.[1][5]

The trachea is a C-shaped structure, flexible tube that is composed of hyaline cartilage on the anterior and lateral walls. The posterior wall of the trachea is formed by the trachealis smooth muscle .Also the trachea is composed of several primary structural annular ligaments.[5] [6]

Hyaline cartilage[edit | edit source]
  1. Series of 16 to 20 hyaline cartilage rings connected by an annular ligament.
  2. The tracheal cartilaginous rings, are responsible for keeping the trachea lumen open in spite of the changes in intrathoracic pressure that occur during respiration.[5]
Trachealis muscle[edit | edit source]
  • Type of muscle : Smooth muscle
  • Connects the ends of the C-shaped tracheal cartilages.
  • Is in contact with the anterior esophagus
  • The trachealis muscle functions to constrict the airway by pulling the cartilages together. By decreasing the diameter of the airway, it allows for increased expiratory force during coughing and thus allows greater velocity to be achieved for the particle to be expelled. This action is helpful, especially when eating food, which requires the expansion of the esophagus.[1]
Figure 3: Cross-section of a trachea

Bronchi[edit | edit source]

At the level of the fifth thoracic vertebra, the trachea divides into the left and right main bronchi. The right main bronchus has a length of 2.5 cm, and the left main bronchus is 5 cm long.

The trachea divides at the carina (at the level of the sternal angle) to give rise to the two primary bronchi – the right and left bronchus (figure 4). Differences between right and left bronchus are illustrated below in table 1 .The right and left bronchus conduct air from the trachea into the right and left lung respectively.

Figure 4: The lower respiratory tract 1:Trachea, 2: Mainstem bronchus 3: Lobar bronchus,4: Segmental bronchus, 5: Bronchiole,6: Alveolar duct, 7:Alveolus

The primary bronchi then branch into secondary bronchi (lobar bronchi) – three on the right and two on the left. Each secondary bronchus supplies a lobe of each lung.

Each secondary bronchi (lobar bronchi) subsequently divide into narrower tertiary bronchi (segmental bronchi) that supply bronchopulmonary segments (largest subdivisions of a lobe).

Segmental bronchi undergo further branching to form numerous smaller airways, called the bronchioles.[6][7]

Right Bronchus
  1. Wider
  2.  More vertical
  3. Shorter (2.5 cm)
  4. Supported by C shaped cartilages
  5. 20 to 30 degree angle
Left Bronchus    
  1. Narrower
  2. More angular
  3. Longer (5cm)
  4. Supported by C shaped cartilages
  5. 40 to 60 degree angle

Table 1[6]

Bronchioles[edit | edit source]

Bronchioles arise from segmental bronchi and represent the smaller branches of the bronchial tree. They differ histologically from bronchi as they lack C shaped cartilages in their walls.[8]

Bronchioles initially divide into many generations of conducting bronchioles which eventually divide further into terminal bronchioles which further divide into respiratory bronchioles.

Conducting bronchioles (part of conducting zone)

  • Segmental bronchi give rise to 20 to 25 generations of conducting bronchioles that further divide to terminal bronchioles.
  • Function - as part of the conducting system they allow air to travel from the trachea to alveoli where gas exchange occurs.

Terminal bronchioles (part of conducting zone)

  • Represent the last part of the conducting part of the bronchial tree and give rise to several generations of respiratory bronchioles
  • Function - as part of the conducting system they allow air to travel from the trachea to alveoli where gas exchange occurs.[6]

Respiratory bronchioles ( part of respiratory zone)

  • Distinguishable to other types of bronchioles by the presence of alveoli extending from their lumens
  • Function - represent the first part of the respiratory airways where they facilitate gas exchange[6]

Gas exchange occurs in the respiratory bronchioles, alveolar ducts and alveoli, which collectively form the respiratory zones deep in the lungs.

[9]

Clinical relevance[edit | edit source]

Physiotherapy plays an important role in most respiratory conditions like asthma , COPD, cystic fibrosis and others. A group of techniques such as active cycles of breathing, huffing, autogenic drainage, coughing, and forced expiratory can be used by physiotherapists to help remove extra mucus from tracheobronchial secretions. Thick or excessive secretions produced by respiratory disorders may become accumulated and as a result may develop bronchial infections. The role of physiotherapy is minimising the symptoms and educating people who have respiratory diseases on how to self manage their symptoms and prevent further complications.

References[edit | edit source]

  1. 1.0 1.1 1.2 1.3 Downey RP, Samra NS. Anatomy, Thorax, Tracheobronchial Tree. InStatPearls [Internet] 2020 Jul 31. StatPearls Publishing.
  2. Gauthier SP, Wolfson MR, Deoras KS, Shaffer TH. Structure-function of airway generations 0 to 4 in the preterm lamb. Pediatric research. 1992 Feb;31(2):157-62.
  3. Patwa A, Shah A. Anatomy and physiology of respiratory system relevant to anaesthesia. Indian journal of anaesthesia. 2015 Sep;59(9):533.
  4. Brand-Saberi BE, Schäfer T. Trachea: anatomy and physiology. Thoracic surgery clinics. 2014 Feb 1;24(1):1-5.
  5. 5.0 5.1 5.2 Mieczkowski B, Seavey BF. Anatomy, Head and Neck, Trachea.
  6. 6.0 6.1 6.2 6.3 6.4 Clinically Oriented Anatomy, Keith L. Moore, Arthur F. Dalley, Anne M. R. Agur, Philadelphia, United States
  7. Eleanor Main & Linda Denehy, Cardiorespiratory Physiotherapy: Adults and paediatrics, 5th Edition
  8. Amador C, Weber C, Varacallo M. Anatomy, thorax, bronchial. InStatPearls [Internet] 2021 Aug 11. StatPearls Publishing. BibTeXEndNoteRefManRefWorks
  9. Meditay.Trachea, Bronchial Tree and Alveolar Tree (Parts, Structures and Walls) - Anatomy Available from:https://www.youtube.com/watch?v=5F8XdE1d0xk