Hodgkin's Lymphoma: Difference between revisions
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== Prevalence == | == Prevalence == | ||
In 2007, there were approximately 164,273 persons in the United States with a history of Hodgkin’s lymphoma. Based on rates from 2005-2007, “1 in 428 men and women will be diagnosed with Hodgkin lymphoma during their lifetime.”8 | |||
Incidence Rates by Race 8<br><br> | |||
{| cellspacing="1" cellpadding="1" border="1" style="width: 465px; height: 246px;" | |||
|+ Incidence Rates by Race | |||
|- | |||
| Race/Ethnicity<br> | |||
| Male<br> | |||
| Female<br> | |||
|- | |||
| All Races<br> | |||
| 3.2 per 100,000<br> | |||
| 2.5 per 100,000<br> | |||
|- | |||
| White<br> | |||
| 3.4 per 100,000<br> | |||
| 2.7 per 100,000<br> | |||
|- | |||
| Black<br> | |||
| 3.0 per 100,000<br> | |||
| 2.3 per 100,000<br> | |||
|- | |||
| Asian/Pacific Islander<br> | |||
| 1.5 per 100,000<br> | |||
| 1.1 per 100,000<br> | |||
|- | |||
| American Indian/Alaska Native<br> | |||
| <br> | |||
| <br> | |||
|- | |||
| Hispanic<br> | |||
| 2.8 per 100,000<br> | |||
| | |||
2.0 per 100,000 | |||
|} | |||
<br> | |||
Hodgkin’s can occur in children and adults at any age, but peaks around age 25-30 years and after 55 years. Men are typically diagnosed with Hodgkin’s more than women. “Children younger than 5 years rarely develop this disease, while only 10% of HL cases occur in children 16 years old and younger.”4 The nodular lymphocyte-predominant Hodgkin’s lymphoma (LPHL), has a peak incidence around the fourth decade of life. | |||
Approximately 7800 cases of HL are diagnosed in the United States each year.4 | |||
“Estimated new cases and deaths from Hodgkin’s lymphoma in the United States in 2010:<br> New cases: 8490<br> Deaths: 1320”6<br><br> | |||
== Characteristics/Clinical Presentation == | == Characteristics/Clinical Presentation == |
Revision as of 04:20, 25 February 2011
Original Editors - Ann Bedwell from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Lead Editors - Your name will be added here if you are a lead editor on this page. Read more.
Definition/Description[edit | edit source]
Hodgkin’s Lymphoma, also known as Hodgkin’s disease, is a “chronic, progressive, neoplastic disorder of lymphatic tissue characterized by the painless enlargement of lymph nodes with progression to extralymphatic sites such as the spleen and liver.”1 It may also metastasize to bone marrow and other organs.2 The sites initially affected are the lymph glands in the neck or groin, usually on one side.
This type of cancer is malignant and may travel to other parts of the body. As it progresses, it may compromise the body’s ability to fight infection since it is attacking the immune system.3
Hodgkin’s lymphoma is differentiated from other cancers and Non-Hodgkin’s lymphoma (connect to page) by the type of cell involved. The Reed-Sternberg cell is “part of the tissue macrophage system and have twin nuclei and nucleoli that give them the appearance of owl eyes.”4 There are two subtypes of Hodgkin’s lymphoma, classic and nodular lymphocyte-predominant. Classic Hodgkin’s lymphoma is further divided into four categories based on what the cell looks like under a microscope. These are Lymphocyte-rich classical Hodgkin lymphoma, Nodular sclerosis Hodgkin lymphoma, Mixed cellularity Hodgkin lymphoma, Lymphocyte-depleted Hodgkin lymphoma.5
Prevalence[edit | edit source]
In 2007, there were approximately 164,273 persons in the United States with a history of Hodgkin’s lymphoma. Based on rates from 2005-2007, “1 in 428 men and women will be diagnosed with Hodgkin lymphoma during their lifetime.”8
Incidence Rates by Race 8
Race/Ethnicity |
Male |
Female |
All Races |
3.2 per 100,000 |
2.5 per 100,000 |
White |
3.4 per 100,000 |
2.7 per 100,000 |
Black |
3.0 per 100,000 |
2.3 per 100,000 |
Asian/Pacific Islander |
1.5 per 100,000 |
1.1 per 100,000 |
American Indian/Alaska Native |
||
Hispanic |
2.8 per 100,000 |
2.0 per 100,000 |
Hodgkin’s can occur in children and adults at any age, but peaks around age 25-30 years and after 55 years. Men are typically diagnosed with Hodgkin’s more than women. “Children younger than 5 years rarely develop this disease, while only 10% of HL cases occur in children 16 years old and younger.”4 The nodular lymphocyte-predominant Hodgkin’s lymphoma (LPHL), has a peak incidence around the fourth decade of life.
Approximately 7800 cases of HL are diagnosed in the United States each year.4
“Estimated new cases and deaths from Hodgkin’s lymphoma in the United States in 2010:
New cases: 8490
Deaths: 1320”6
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Case Reports/ Case Studies[edit | edit source]
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Hodgkin's lymphoma masquerading as vertebral osteomyelitis in a man with diabetes: a case report
Hodgkin's lymphoma presenting with heart failure: a case report
Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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