Pulmonary Complications of Cancer: Difference between revisions

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Cancer patients are susceptible to infection, particularly those undergoing chemotherapy and radiation therapy. Aside from that, there are a variety of factors that predisposes the cancer patient to infection such as immune deficiencies, organ dysfunction, concurrent illness and past infections, nutritional status, psychological stress, surgery and diagnostic and invasive procedures.<ref>Stosor V, Zembower TR, editors. Infectious Complications in Cancer Patients. Springer; 2014. </ref>
Cancer patients are susceptible to infection, particularly those undergoing chemotherapy and radiation therapy. Aside from that, there are a variety of factors that predisposes the cancer patient to infection such as immune deficiencies, organ dysfunction, concurrent illness and past infections, nutritional status, psychological stress, surgery and diagnostic and invasive procedures.<ref>Stosor V, Zembower TR, editors. Infectious Complications in Cancer Patients. Springer; 2014. </ref>


Bacterial Infection
=== Bacterial Infection ===
Bacterial infection in cancer patients present in the form of pneumonia.
 
Common bacterial pathogens:
* Streptococcus pneumoniae
* Haemophilus influenzae
* Pseudomonas aeruginosa
* Escherichia coli
* Klebsiella species
* Legionella pneumophila
* Mycoplasma pneumoniae
* Nocardia and Actinomyces species
* Moraxella catarrhalis


Viral Infection
Viral Infection

Revision as of 03:37, 4 July 2020

Original Editor - Donald John Auson Top Contributors - Donald John Auson and Kim Jackson
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Infectious Complications[edit | edit source]

Cancer patients are susceptible to infection, particularly those undergoing chemotherapy and radiation therapy. Aside from that, there are a variety of factors that predisposes the cancer patient to infection such as immune deficiencies, organ dysfunction, concurrent illness and past infections, nutritional status, psychological stress, surgery and diagnostic and invasive procedures.[1]

Bacterial Infection[edit | edit source]

Bacterial infection in cancer patients present in the form of pneumonia.

Common bacterial pathogens:

  • Streptococcus pneumoniae
  • Haemophilus influenzae
  • Pseudomonas aeruginosa
  • Escherichia coli
  • Klebsiella species
  • Legionella pneumophila
  • Mycoplasma pneumoniae
  • Nocardia and Actinomyces species
  • Moraxella catarrhalis

Viral Infection

Fungal Infection

Protozoal Infection

Non-Infectious Complications

Metastatic Disease

Obstructive Lung Disease

Restrictive Lung Disease

Radiation Therapy Complications

Radiation Pneumonitis

Chemotherapy Complications

Chemotherapy Pneumonitis

Pulmonary Vascular Disease

Drug Toxicities

Certain drugs have been shown to increase the risk for the development of pulmonary complications such as respiratory failure.[2] This include tyrosine kinase inhibitors, mTOR kinase inhibitors, monoclonal antibody, taxanes.  A study showed that exposure to one of more of these medications was a significant risk factor in the development of respiratory failure.[2]

Rehabilitation Treatment

Considerations

  1. Stosor V, Zembower TR, editors. Infectious Complications in Cancer Patients. Springer; 2014.
  2. 2.0 2.1 Brown, Anne Rain; Bruno, Jeffrey; Nates, Joseph 1239: PULMONARY COMPLICATIONS IN CANCER PATIENTS: NOVEL DRUGS WITH NEW TOXICITIES, Critical Care Medicine: January 2018 - Volume 46 - Issue 1 - p 603 doi: 10.1097/01.ccm.0000529242.93804.d6 Available at https://journals.lww.com/ccmjournal/Citation/2018/01001/1239__PULMONARY_COMPLICATIONS_IN_CANCER_PATIENTS_.1193.aspx