Reactive Arthritis: Difference between revisions
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== Differential Diagnosis == | == Differential Diagnosis == | ||
*Psoriasis | |||
*Pityriasis rubra pilaris | |||
*Lichen planus | |||
*Lupus Erythematosus | |||
*Dermatomyositis | |||
*Behcet's disease | |||
*Arthritis associated with gonococcal disease | |||
*Rheumatoid arthritis | |||
*Septic Arthritis | |||
*Mycosis fungoides | |||
*Subcorneal pustulosis of Sneddon-Wilkinson | |||
*Atopic dermatitis | |||
*Acute exanthematous pustulosis | |||
*other causes of erythroderma | |||
== Case Reports == | == Case Reports == |
Revision as of 19:11, 20 March 2010
Original Editors - Jennifer Colgan from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Lead Editors - Your name will be added here if you are a lead editor on this page. Read more.
Definition/Description[edit | edit source]
Reiter’s Syndrome is an autoimmune condition that develops in response to infection. It is marked by inflammatory synovitis and erosion at the insertion sites of ligaments and tendons. It is often referred to as reactive arthritis that follows an infection elsewhere in the body primarily in HLA-B27-positive individuals.
Prevalence[edit | edit source]
Prevalence is difficult to establish due to lack of consensus regarding diagnostic criteria, the nomadic nature of the young target population, the underreporting of venereal disease, and the asymptomatic or milder course in affected women.
Characteristics/Clinical Presentation Peak onset occurs in the third decade of life and more commonly affects males.
Three major symptoms associated with Reiter's Syndrome: Urethritis, conjunctivitis, and arthritis
The arthritis is usually asymmetrical and typically involves joints in the lower extremities.
Musculoskeletal manifestation include:acute inflammatory arthritis, inflammatory back pain, and enthesitis
Skin lesions are very similar to those of psoriasis.
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
There is no evidence that antibiotic therapy changes the course of the disorder. NSAIDS are the primary intervention.
Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
Due to various manifestations of the disease occurring at different times, a diagnosis may take months to establish. The combination of peripheral arthritis with urethritis lasting longer than 1 month is necessary before the diagnosis can be confirmed. Laboratory tests typically reveal an aggressive inflammatory process. Elevated ESR and C-reactive protein are detected, and thrombocytosis and leukocytes are common findings. Urine samples, genital swabs, and stool cultures are useful laboratory tests for identifying the triggering infection. Radiographic abnormalities may include asymmetric involvement of the lower extremity diarthroses, amphiarthroses, symphyses, and enthuses. Also, ill defined bony erosions with adjacent bony proliferation or paravertebral ossiciation may show
Causes[edit | edit source]
Reiter’s syndrom usually follows venereal disease or an episode of bacillary dysentery (enteric infection). Up to 85% of people with Reiter's possess the HLA-B27 alloantigen. Individuals with the appropriate genetic background can develop reactive arthritis by an enteric infectipon.
Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
- Psoriasis
- Pityriasis rubra pilaris
- Lichen planus
- Lupus Erythematosus
- Dermatomyositis
- Behcet's disease
- Arthritis associated with gonococcal disease
- Rheumatoid arthritis
- Septic Arthritis
- Mycosis fungoides
- Subcorneal pustulosis of Sneddon-Wilkinson
- Atopic dermatitis
- Acute exanthematous pustulosis
- other causes of erythroderma
Case Reports[edit | edit source]
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Resources
[edit | edit source]
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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