Paget's Disease: Difference between revisions
No edit summary |
No edit summary |
||
| Line 11: | Line 11: | ||
Goodman C, Fuller K. Pathology: Implications for the Physical Therapist. St. Louis, Missouri: Saunders Elsevier;2009. | Goodman C, Fuller K. Pathology: Implications for the Physical Therapist. St. Louis, Missouri: Saunders Elsevier;2009. | ||
Josse R, Hanley D, Kendler D, Marie LG, Adachi J, Brown J. "Diagnosis and Treatment of Paget's Disease of the Bone". Clin Invest Med August 2007: E210-E223. | Josse R, Hanley D, Kendler D, Marie LG, Adachi J, Brown J. "Diagnosis and Treatment of Paget's Disease of the Bone". Clin Invest Med August 2007: E210-E223. | ||
Goodman C, Snyder T. Differential Diagnosis for Physical Therapists: Screening for Referral. St. Louis, Missouri: Saunders Elsevier, 2007. | Goodman C, Snyder T. Differential Diagnosis for Physical Therapists: Screening for Referral. St. Louis, Missouri: Saunders Elsevier, 2007. | ||
Revision as of 19:54, 21 February 2010
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Lead Editors - Your name will be added here if you are a lead editor on this page. Read more.
Definition/Description[edit | edit source]
Also known as Osteitis Deformans, Paget's disease of the bone is a metabolic bone disease caused by increased bone resorption followed by excessive unrestricted bone formation, due to activated osteoclasts. The normal bone marrow is replaced by increased and unorganized collagen and fibrous tissue, which lacks the structural stability of normal bone. This increased bone mass formation leads to complications such as fractures, arthritis, deformities, and pain due to its weakened condition.
Goodman C, Fuller K. Pathology: Implications for the Physical Therapist. St. Louis, Missouri: Saunders Elsevier;2009.
Josse R, Hanley D, Kendler D, Marie LG, Adachi J, Brown J. "Diagnosis and Treatment of Paget's Disease of the Bone". Clin Invest Med August 2007: E210-E223.
Goodman C, Snyder T. Differential Diagnosis for Physical Therapists: Screening for Referral. St. Louis, Missouri: Saunders Elsevier, 2007.
Prevalence[edit | edit source]
After Osteoporosis, Paget's disease is the most common skeletal disorder. Paget's disease affects approximately 2% to 5% of the population older than 40, and seen in 10% of the population over the age of 70 years old. Paget's disease affects men more than woman by a 3:2 ratio. Evidence has shown that genetic factors of 40% of the individuals with Paget's disease have first-degree relatives with Paget's disease. Recently, the prevalence of Paget's disease has decreased by 50% of the prevalence in 1983.
Characteristics/Clinical Presentation[edit | edit source]
add text here
Associated Co-morbidities[edit | edit source]
add text here
Medications[edit | edit source]
add text here
Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
add text here
Causes[edit | edit source]
add text here
Systemic Involvement[edit | edit source]
add text here
Medical Management (current best evidence)[edit | edit source]
add text here
Physical Therapy Management (current best evidence)[edit | edit source]
add text here
Alternative/Holistic Management (current best evidence)[edit | edit source]
add text here
Differential Diagnosis[edit | edit source]
add text here
Case Reports[edit | edit source]
add links to case studies here (case studies should be added on new pages using the case study template)
Resources
[edit | edit source]
add appropriate resources here
Recent Related Research (from Pubmed)[edit | edit source]
see tutorial on Adding PubMed Feed
Extension:RSS -- Error: Not a valid URL: Feed goes here!!|charset=UTF-8|short|max=10
References[edit | edit source]
see adding references tutorial.
