End Organ: Difference between revisions

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'''Original Editor '''- [[User:User Name|User Name]]
'''Original Editor '''- [[User:Lucinda hampton|Lucinda hampton]]


'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}}  &nbsp;   
'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}}  &nbsp;   
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An end organ is the last  organ affected in a chain of events, for instance a disease process.  
An end organ is the last  organ affected in a chain of events, for instance a disease process.  


Examples are the liver, brain or kidney, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.
Examples are the liver, brain, kidney or heart, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.


== Sub Heading 2 ==
== Detection ==
A pathological change in the microcirculation plays a pivotal role in promoting end-organ dysfunction that not only predisposes to further organ damage, but also increases the risk for future macrovascular events.  
Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.  


* Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
Classical pointers for end organ damage include:
* Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
* Similar to arterial hypertension and obesity, type 2 diabetes mellitus is associated with target organ damage


== Sub Heading 3 ==
* Stoke, vascular and hemorrhagic
* Retinopathy
* Coronary heart disease/myocardial infarction and heart failure
* Proteinuria
* Renal failure
* Atherosclerotic change eg stenoses and aneurysms in the blood vessels.<ref>Schmieder RE. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ End organ damage in hypertension.] Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)</ref>


== Resources  ==
== Risk Factors ==
*bulleted list
Many and varied and include:
*x
or


#numbered list
# Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
#x
# Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
# Type 2 diabetes mellitus is associated with target organ damage


== Viewing ==
Watch this 1 mi nute video with information tables regarding "Assessing damage to major organs due to hypertension".{{#ev:youtube|v=WVFbsgg1c_Q}}<ref>MediBuddy - Your Health Friend. End organ damage in Hypertension | Hypertension Update | Dr Adrija | CME Session | MediBuddy. Available from: https://www.youtube.com/watch?v=WVFbsgg1c_Q [last accessed 9.5.2024]</ref>
== References  ==
== References  ==


<references />
<references />

Revision as of 08:48, 9 May 2024

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton  

Introduction[edit | edit source]

An end organ is the last organ affected in a chain of events, for instance a disease process.

Examples are the liver, brain, kidney or heart, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.

Detection[edit | edit source]

Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.

Classical pointers for end organ damage include:

  • Stoke, vascular and hemorrhagic
  • Retinopathy
  • Coronary heart disease/myocardial infarction and heart failure
  • Proteinuria
  • Renal failure
  • Atherosclerotic change eg stenoses and aneurysms in the blood vessels.[1]

Risk Factors[edit | edit source]

Many and varied and include:

  1. Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
  2. Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
  3. Type 2 diabetes mellitus is associated with target organ damage

Viewing[edit | edit source]

Watch this 1 mi nute video with information tables regarding "Assessing damage to major organs due to hypertension".

[2]

References[edit | edit source]

  1. Schmieder RE. End organ damage in hypertension. Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)
  2. MediBuddy - Your Health Friend. End organ damage in Hypertension | Hypertension Update | Dr Adrija | CME Session | MediBuddy. Available from: https://www.youtube.com/watch?v=WVFbsgg1c_Q [last accessed 9.5.2024]