Hidradenitis Suppurativa

Original Editor - Samuel Mayah

Top Contributors - Samuel Mayah and Kirenga Bamurange Liliane  

Introduction[edit | edit source]

Hidradenttis Suppurative.jpg

Hidradenitis suppurativa is a chronic inflammatory condition that is often debilitating, causing extreme pain, abscesses, sinus tract formation, and scarring it affects the follicular epithelium in various areas of the body, including the axillae, buttocks, inguinal, perianal, and sub mammary regions. It is a recurrent disease characterized by apocrine-bearing skin involvement, particularly in intertriginous areas such as the genital skin. The disease can cause significant distress, loss of confidence, and poor quality of life, with adverse effects on sexual life.

Causes[edit | edit source]

The etiology of HS is multifactorial, involving a combination of genetic, hormonal, and environmental factors. The exact cause of HS is not fully understood, but several factors have been identified as potential contributors. HS is more common in females and typically occurs in early adulthood Risk factors such as smoking, consumption of dairy products, and carbohydrates have also been associated with HS.

Signs/symptoms of Hidradenitis suppurativa[edit | edit source]

It is characterized by inflamed skin nodules, abscesses, pus discharge tunnels, and scarring in areas such as the axillae, groin, and perineal region. The signs and symptoms of HS include pain, pruritus, malodour, and suppuration. These symptoms can have a significant impact on the quality of life of HS patients, affecting general well-being, sexual distress, anxiety, depression, and sleep. The severity of these symptoms correlates with poorer quality of life. The assessment of signs and symptoms in HS patients should be thorough and included in routine evaluations to guide therapeutic modifications and improve patients' health.

Resources[edit | edit source]

References[edit | edit source]

  • Heath, C.R. and Usatine, R.P., 2022. Hidradenitis suppurativa. The Journal of family practice, 71(7), pp.E17-E18.
  • Wiseman, M.C., 2004. Hidradenitis suppurativa: a review. Dermatologic therapy, 17(1), pp.50-54.
  • Lupu, M., Voicu, C., Papagheorghe, L., Tudose, I. and Gabriel, V., 2015. HIDRADENITIS SUPPURATIVA: A REVIEW OF PATHOGENESIS AND TREATMENT HIDRADENITA SUPURATIVĂ: O ANALIZĂ A PATOGENIEI ȘI TRATAMENTULUI. Romanian Journal of Clinical and Experimental Dermatology, 2(1).
  • Anduquia-Garay, F., Rodríguez-Gutiérrez, M.M., Poveda-Castillo, I.T., Valdes-Moreno, P.L., Agudelo-Rios, D.A., Benavides-Moreno, J.S., Lozada-Martínez, I.D., Bolaño-Romero, M.P., Borraez-Segura, B. and Rahman, S., 2021. Hidradenitis suppurativa: Basic considerations for its approach: A narrative review. Annals of Medicine and Surgery, 68, p.102679.
  • Jenkins, T., Isaac, J., Edwards, A. and Okoye, G.A., 2023. Hidradenitis suppurativa. Dermatologic Clinics.
  • Goldburg, S.R., Strober, B.E. and Payette, M.J., 2020. Hidradenitis suppurativa: epidemiology, clinical presentation, and pathogenesis. Journal of the American Academy of Dermatology, 82(5), pp.1045-1058.
  • Luporini, R.L., Frizol, S.M., Segantini, M.J., Pereira, L.D., Fontanella, A.P. and Féres, O., 2022. Hidradenitis suppurativa perineal and perianal. In Benign Anorectal Disorders-An Update. IntechOpen.
  • Wendel, A., Paleo for Autoimmune Illness. Robb Wolf.
  • Cotton, C.H., Chen, S.X., Hussain, S.H., Lara-Corrales, I. and Zaenglein, A.L., 2023. Hidradenitis Suppurativa in Pediatric Patients. Pediatrics, 151(5), p.e2022061049.
  • Teplyuk, N.P. and Pirogova, A.S., 2022. Photogallery. Hidradenitis suppurativa (acne inversa). Russian Journal of Skin and Venereal Diseases, 25(4), pp.337-340.
  • Heath, C.R. and Usatine, R.P., 2022. Hidradenitis suppurativa. The Journal of family practice, 71(7), pp.E17-E18.
  • van Straalen, K.R., Ingram, J.R., Augustin, M. and Zouboulis, C.C., 2022. New treatments and new assessment instruments for hidradenitis suppurativa. Experimental Dermatology, 31, pp.33-39.
  • Shukla, R., Karagaiah, P., Patil, A., Farnbach, K., Ortega-Loayza, A.G., Tzellos, T., Szepietowski, J.C., Giulini, M., Schepler, H., Grabbe, S. and Goldust, M., 2022. Surgical treatment in hidradenitis suppurativa. Journal of Clinical Medicine, 11(9), p.2311.