Ataxia In Cerebral Palsy
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Clinically Relevant Anatomy
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Mechanism of Injury / Pathological Process
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Ataxia " is defined as an inability to generate a normal or expected voluntary movement trajectory that cannot be attributed to weakness or involuntary muscle activity about the affected joints.[1]
An important aspect of the cerebellum's function is highlighted by Justus et. al as"... memory processes required for associative learning and adapting of motor functions"[2] In addition, recent research has also shown the cerebellum's involvement in autonomic, emotional and even cognitive aspects of brain function.[3]
Clinical Presentation[edit | edit source]
Diagnostic Procedures[edit | edit source]
Magnetic resonance imaging (MRI) is considered the general standard of diagnosing CP in general.[4] However, a study done in 2022 highlighted the fact that despite the 31 CP children enrolled in their study displaying no structural abnormalities on MRI, these children did display abnormalities in terms of cerebral glucose metabolism on PET (position emission tomography) scans. [5]
Outcome Measures[edit | edit source]
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Management / Interventions
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Differential Diagnosis
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Resources
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References[edit | edit source]
- ↑ Sanger TD, Chen D, Delgado MR, Gaebler-Spira D, Hallett M, Mink JW, Taskforce on Childhood Motor Disorders. Definition and classification of negative motor signs in childhood. Pediatrics. 2006 Nov 1;118(5):2159-67.
- ↑ Kebschull JM, Casoni F, Consalez GG, Goldowitz D, Hawkes R, Ruigrok TJ, Schilling K, Wingate R, Wu J, Yeung J, Uusisaari MY. Cerebellum lecture: the cerebellar nuclei—core of the cerebellum. The Cerebellum. 2023 Feb 13:1-58. Pg 2
- ↑ Kebschull JM, Casoni F, Consalez GG, Goldowitz D, Hawkes R, Ruigrok TJ, Schilling K, Wingate R, Wu J, Yeung J, Uusisaari MY. Cerebellum lecture: the cerebellar nuclei—core of the cerebellum. The Cerebellum. 2023 Feb 13:1-58.
- ↑ Arnfield E, Guzzetta A, Boyd R. Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: a systematic review. Research in Developmental Disabilities. 2013 Jul 1;34(7):2234-50.
- ↑ Wu R, Gao Y, Zhang H, Chen Y, Tan F, Zeng D, Wan H, Yang Y, Gu J, Pei Z. Metabolic assessment of cerebral palsy with normal clinical MRI using 18F-FDG PET imaging: A preliminary report. Frontiers in Neurology. 2022 Sep 15;13:844911.
