Whipple Disease
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Top Contributors - Aya Alhindi
Introduction[edit | edit source]
Whipple's disease is a rare, chronic, systemic infectious disorder caused by a gram-positive intracellular bacterium, Tropheryma whipplei (TW).[1][2]The disorder can affect any system in the body but most commonly with prominent intestinal manifestations.[3] The patient exhibits the classically described signs of malabsorption caused by gastrointestinal colonization. However, it can exhibit clinically overlapping signs and symptoms with rheumatic diseases, potentially leading to misdiagnosis.[4]
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References[edit | edit source]
- ↑ El-Abassi R, Soliman MY, Williams F, England JD. Whipple’s disease. J Neurol Sci [Internet]. 2017;377:197–206.
- ↑ Tison A, Preuss P, Leleu C, Robin F, Le Pluart A, Vix J, et al. Rheumatological features of Whipple disease. Sci Rep [Internet]. 2021;11(1):12278.
- ↑ 1. Whipple’s Disease [Internet]. National Institute of Neurological Disorders and Stroke.
- ↑ Kukull B, Mahlow J, Hale G, Perry LJ. Whipple’s disease: a fatal mimic. Autops Case Rep [Internet]. 2021;11:e2020237.