The influence of marijuana on physiologic processes and exercise: Difference between revisions

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&nbsp;Cannabis use is widespread, totaling more than 400 possible compounds with the most prevalent compound being THC&nbsp;. THC has a psychotropic effect on the central nervous system by acting on CB1 and an analgesic by working on CB2 receptors. CB1/CB2 receptors are activated by the attachment of the ligand, Anandamide <ref name="Pesta">Pesta, H. D., Angadi, S. S., Burtscher, M., &amp;amp;amp;amp;amp;amp;amp;amp;amp; Roberts, K. C. (2013). The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance. Nutrition &amp;amp;amp;amp;amp;amp;amp;amp;amp; Metabolism. 10(71). doi: 10.1186/1743-7075-10-71</ref> . Marijuana has been shown to elevate resting heart rate and systolic/diastolic pressure after consumption <ref>Steadward, R. D., &amp;amp;amp;amp;amp;amp;amp;amp;amp; Singh, M. (1975). The effects of smoking marihuana on physical performance. Med Sci Sports. 7(4)</ref> . Marijuana has also been seen to produce bronchodilation in patients with bronchoconstriction secondary to asthma <ref>Vachon L., FitzGerald, M. X., Soliday, N.H., Gould, I. A. &amp;amp;amp;amp;amp;amp;amp;amp;amp; Gaensler E. A. (1973) Single-dose effects of marihuana smoke. Bronchial dynamics and respiratory-center sensitivity in normal subjects.N Engl J Med. 10; 288(19):985-9.</ref> . Many athletes consume marijuana for their euphoric effects by reducing stress and anxiety. By reducing stress before competition allows for adequate sleep, which allows for optimal performance <ref name="Pesta" />&nbsp;.  
&nbsp;Cannabis use is widespread, totaling more than 400 possible compounds with the most prevalent compound being THC&nbsp;. THC has a psychotropic effect on the central nervous system by acting on CB1 and an analgesic by working on CB2 receptors. CB1/CB2 receptors are activated by the attachment of the ligand, Anandamide <ref name="Pesta">Pesta, H. D., Angadi, S. S., Burtscher, M., &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp; Roberts, K. C. (2013). The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance. Nutrition &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp; Metabolism. 10(71). doi: 10.1186/1743-7075-10-71</ref> . Marijuana has been shown to elevate resting heart rate and systolic/diastolic pressure after consumption <ref>Steadward, R. D., &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp; Singh, M. (1975). The effects of smoking marihuana on physical performance. Med Sci Sports. 7(4)</ref> . Marijuana has also been seen to produce bronchodilation in patients with bronchoconstriction secondary to asthma <ref>Vachon L., FitzGerald, M. X., Soliday, N.H., Gould, I. A. &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp; Gaensler E. A. (1973) Single-dose effects of marihuana smoke. Bronchial dynamics and respiratory-center sensitivity in normal subjects.N Engl J Med. 10; 288(19):985-9.</ref> . Many athletes consume marijuana for their euphoric effects by reducing stress and anxiety. By reducing stress before competition allows for adequate sleep, which allows for optimal performance <ref name="Pesta" />&nbsp;.  


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&nbsp; &nbsp;Marijuana, through THC, increases a person's heart rate, raises supine blood pressure a bit, and can bring about orthostatic hypotension. &nbsp;As a person continually exposes themselves to marijuana, the tension disappears, a&nbsp;person’s blood volume will go up, and their circulatory system response goes down. Users show tolerance to these initial effects quickly. These effects do not usually bring about serious health problems for users who are young and healthy. Stroke, heart attack, and other cardiac problems occasionally happen. People who have cardiovascular disease are much more likely to have health problems because their heart has to work harder, their catecholamine levels go up, and postural hypotension happens. <ref>Jones, R.T.  (2002).  Cardiovascular effects of marijuana.  J CLin. Pharmacol. 42(11), 58-63</ref>  
Marijuana, through THC, increases a person's heart rate, raises supine blood pressure a bit, and can bring about orthostatic hypotension. Users show tolerance to these initial effects quickly. As a person continually exposes themselves to marijuana, the tension disappears, a person's blood volume will go up, and their circulatory response goes down. These effects do not usually bring about serious health problems for users who are young and healthy. Stroke, heart attack, and other heart problems have been known to happen occasionally. People who have cardiovascular disease are much more likely to have health problems because their heart has to work harder, their catecholamine levels go up, and postural hypotension happens.<ref>Jones, R.T.  (2002).  Cardiovascular effects of marijuana.  J CLin. Pharmacol. 42(11), 58-63</ref>


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Revision as of 02:02, 11 November 2015

 Cannabis use is widespread, totaling more than 400 possible compounds with the most prevalent compound being THC . THC has a psychotropic effect on the central nervous system by acting on CB1 and an analgesic by working on CB2 receptors. CB1/CB2 receptors are activated by the attachment of the ligand, Anandamide [1] . Marijuana has been shown to elevate resting heart rate and systolic/diastolic pressure after consumption [2] . Marijuana has also been seen to produce bronchodilation in patients with bronchoconstriction secondary to asthma [3] . Many athletes consume marijuana for their euphoric effects by reducing stress and anxiety. By reducing stress before competition allows for adequate sleep, which allows for optimal performance [1] .


  1. 1.0 1.1 Pesta, H. D., Angadi, S. S., Burtscher, M., &amp;amp;amp;amp;amp;amp;amp;amp;amp; Roberts, K. C. (2013). The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance. Nutrition &amp;amp;amp;amp;amp;amp;amp;amp;amp; Metabolism. 10(71). doi: 10.1186/1743-7075-10-71
  2. Steadward, R. D., &amp;amp;amp;amp;amp;amp;amp;amp;amp; Singh, M. (1975). The effects of smoking marihuana on physical performance. Med Sci Sports. 7(4)
  3. Vachon L., FitzGerald, M. X., Soliday, N.H., Gould, I. A. &amp;amp;amp;amp;amp;amp;amp;amp;amp; Gaensler E. A. (1973) Single-dose effects of marihuana smoke. Bronchial dynamics and respiratory-center sensitivity in normal subjects.N Engl J Med. 10; 288(19):985-9.







Marijuana, through THC, increases a person's heart rate, raises supine blood pressure a bit, and can bring about orthostatic hypotension. Users show tolerance to these initial effects quickly. As a person continually exposes themselves to marijuana, the tension disappears, a person's blood volume will go up, and their circulatory response goes down. These effects do not usually bring about serious health problems for users who are young and healthy. Stroke, heart attack, and other heart problems have been known to happen occasionally. People who have cardiovascular disease are much more likely to have health problems because their heart has to work harder, their catecholamine levels go up, and postural hypotension happens.[1]

  1. Jones, R.T. (2002). Cardiovascular effects of marijuana. J CLin. Pharmacol. 42(11), 58-63