Skeletal muscle function in older people: Difference between revisions

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'''Original Editors '''- [[User:Saeed Dokhnan|Saeed Dokhnan]]


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'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}} &nbsp;
 
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Introduction
 
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= Introduction &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;  =


Aging effects all body organs and systems , one of these systems which we consider to discuss in this page is the skeletal muscle, there are many changes that occur to the muscular system due to aging process,.  
Aging effects all body organs and systems , one of these systems which we consider to discuss in this page is the skeletal muscle, there are many changes that occur to the muscular system due to aging process,.  
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In the aged motor unit there are decreased in the number of functional motor units associated with enlargement of the Cross sectional area of the remaining units, this motor unit remodelling is achieved by selective denervation of muscle fibers, especially type 2 b fibres, followed by re-ennervation by axonal spouting from juxtaposed innervation units  
In the aged motor unit there are decreased in the number of functional motor units associated with enlargement of the Cross sectional area of the remaining units, this motor unit remodelling is achieved by selective denervation of muscle fibers, especially type 2 b fibres, followed by re-ennervation by axonal spouting from juxtaposed innervation units  


= Effect of aging on the muscle =
= Effect of aging on the muscle =


== Muscle strength: ==
== Muscle strength: ==


Muscle strength Muscle strength is reduced with age advances, generally weakness starts in the 3rd decade of life and progress with individual goes older, estimated 8% / decade the muscle strength will decrease<ref>Schiller et al 2000</ref><br>
Muscle strength Muscle strength is reduced with age advances, generally weakness starts in the 3rd decade of life and progress with individual goes older, estimated 8% / decade the muscle strength will decrease<ref>Schiller et al 2000</ref><br>  


== FACTORS AFFECTING MUSCLE STRENGTH  ==
== FACTORS AFFECTING MUSCLE STRENGTH  ==
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3. Incease fat deposition which substitutes muscle fibers  
3. Incease fat deposition which substitutes muscle fibers  


== SPEED OF CONTRACION: ==
== SPEED OF CONTRACION: ==


Velocity of muscle fibers to contract in response to motor nerve firing is decreased which leads to overall decrease in muscle contraction time  
Velocity of muscle fibers to contract in response to motor nerve firing is decreased which leads to overall decrease in muscle contraction time  
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as the aging muscle advances the ability of muscle capillary system to carry out muscle nutrition is deceased, &nbsp;thereby the endurance drop and muscle fatigue easily occur.  
as the aging muscle advances the ability of muscle capillary system to carry out muscle nutrition is deceased, &nbsp;thereby the endurance drop and muscle fatigue easily occur.  


== MUSCLE MASS ==
== MUSCLE MASS ==


aging process wigh physically inactive people will have muscle mass destruction and theire muscles become hypotrophy, these can be delayed by been physically active.  
aging process wigh physically inactive people will have muscle mass destruction and theire muscles become hypotrophy, these can be delayed by been physically active.  


== PROTEIN METABOLISM ==
== PROTEIN METABOLISM ==
 
protein synthesis decreases with age advance and the balance between synthesis and breakdown is disturbed<br>


= Recent related research(from pubmed) =
protein synthesis decreases with age advance and the balance between synthesis and breakdown is disturbed<br>


= Recent related research(from pubmed)  =


http://www.ncbi.nlm.nih.gov/pubmed/24948676
http://www.ncbi.nlm.nih.gov/pubmed/24948676  


http://www.ncbi.nlm.nih.gov/pubmed/24903024
http://www.ncbi.nlm.nih.gov/pubmed/24903024  


= References  =
= References  =


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Revision as of 12:01, 13 July 2014

Original Editors - Saeed Dokhnan

Top Contributors - Saeed Dokhnan, Kim Jackson and Lucinda hampton  

Introduction

Aging effects all body organs and systems , one of these systems which we consider to discuss in this page is the skeletal muscle, there are many changes that occur to the muscular system due to aging process,.

By the age of 80, 40-50% of muscle sstrength, muscle mass, alpha motor neurons and muscle cell are lost. [1]

In  this page we will highlight the most important changes to muscles which affect their performances, and as the muscle and motor unit are interrelated to each other it is important to include the motor unit in this process

Effect of aging on the Motor Unit[edit | edit source]

In the aged motor unit there are decreased in the number of functional motor units associated with enlargement of the Cross sectional area of the remaining units, this motor unit remodelling is achieved by selective denervation of muscle fibers, especially type 2 b fibres, followed by re-ennervation by axonal spouting from juxtaposed innervation units

Effect of aging on the muscle[edit | edit source]

Muscle strength:[edit | edit source]

Muscle strength Muscle strength is reduced with age advances, generally weakness starts in the 3rd decade of life and progress with individual goes older, estimated 8% / decade the muscle strength will decrease[2]

FACTORS AFFECTING MUSCLE STRENGTH[edit | edit source]

1. Exercise,  will iprove muscle strength

2. Diet,   proper diet will postponed the aging process

3. Trauma will increase muscle fiber degeneration

FEATURES of aged muscle:[edit | edit source]

1. Weakness

2. Decrease muscle mass

3. Decrease capillaries and blood supply to the muscle fibers

3. Incease fat deposition which substitutes muscle fibers

SPEED OF CONTRACION:[edit | edit source]

Velocity of muscle fibers to contract in response to motor nerve firing is decreased which leads to overall decrease in muscle contraction time

MUSCLE ENDURANCE[edit | edit source]

as the aging muscle advances the ability of muscle capillary system to carry out muscle nutrition is deceased,  thereby the endurance drop and muscle fatigue easily occur.

MUSCLE MASS[edit | edit source]

aging process wigh physically inactive people will have muscle mass destruction and theire muscles become hypotrophy, these can be delayed by been physically active.

PROTEIN METABOLISM[edit | edit source]

protein synthesis decreases with age advance and the balance between synthesis and breakdown is disturbed

Recent related research(from pubmed)[edit | edit source]

http://www.ncbi.nlm.nih.gov/pubmed/24948676

http://www.ncbi.nlm.nih.gov/pubmed/24903024

References[edit | edit source]

  1. Timothy L.et.al 2007
  2. Schiller et al 2000

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