Scale for the Assessment and Rating of Ataxia (SARA): Difference between revisions

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== Objective<br>  ==
== Objective<br>  ==


SARA is a clinical scale developed by Schmitz-Hübsch et al which assesses a range of diffierent impairments in cerebellar ataxia. The scale is made up of 8 items related to gait, stance, sitting, speech, finger-chase test, nose-finger test, fast alternating movements and heel-shin test.<ref name="Weyer et al">Weyer A, Abele M, Schmitz-Hubsch T, Schoch B, Frings M, Timmann D. Reliability And validity of the scale for the assessment and rating of ataxia: a study in 64 Ataxia patients. Movement Disorders 2007;22:1633–7</ref> Schmitz-Hübsch et al developed the Scale for the Assessment and Rating of Ataxia (SARA) as an alternative to The International Cooperative Ataxia Rating Scale (ICARS). The daily use of ICARS scale in ataxic patients is difficult due to its many assessment items.<ref>Trouillas P, Takayanagi T, Hallett M, Currier RD, Subramony SH, Wessel K, Bryer A, Diener HC, Massaquoi S, Gomez CM, et al. The Ataxia Neuropharmacology Committee of the World Federation of Neurology. International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. J Neurol Sci. 1997;145:205–211.</ref> This new assessment tool has fewer assessment items than the ICARS and therefore has the advantage of easier daily assessment of ataxia. <ref>Schmitz-Hübsch T, du Montcel ST, Baliko L, Berciano J, Boesch S, Depondt C, Giunti P, Globas C, Infante J, Kang JS, et al. Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66:1717–1720.</ref>  
SARA is a clinical scale developed by Schmitz-Hübsch et al which assesses a range of diffierent impairments in cerebellar ataxia. The scale is made up of 8 items related to gait, stance, sitting, speech, finger-chase test, nose-finger test, fast alternating movements and heel-shin test.<ref name="Weyer et al">Weyer A, Abele M, Schmitz-Hubsch T, Schoch B, Frings M, Timmann D. Reliability And validity of the scale for the assessment and rating of ataxia: a study in 64 Ataxia patients. Movement Disorders 2007;22:1633–7</ref> Schmitz-Hübsch et al developed the Scale for the Assessment and Rating of Ataxia (SARA) as an alternative to The International Cooperative Ataxia Rating Scale (ICARS). The daily use of ICARS scale in ataxic patients is difficult due to its many assessment items.<ref>Trouillas P, Takayanagi T, Hallett M, Currier RD, Subramony SH, Wessel K, Bryer A, Diener HC, Massaquoi S, Gomez CM, et al. The Ataxia Neuropharmacology Committee of the World Federation of Neurology. International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. J Neurol Sci. 1997;145:205–211.</ref> This new assessment tool has fewer assessment items than the ICARS and therefore has the advantage of easier daily assessment of ataxia. <ref name="Schmitz et al">Schmitz-Hübsch T, du Montcel ST, Baliko L, Berciano J, Boesch S, Depondt C, Giunti P, Globas C, Infante J, Kang JS, et al. Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66:1717–1720.</ref>  


== Intended Population<br>  ==
== Intended Population<br>  ==
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- Spinocerebellar Ataxia<br>- Ataxic Stroke <ref name="Kim et al">Kim BR, Lim JH, Lee SA, Park S, Koh SE, Lee IS, Jung H, Lee J.Usefulness Of the Scale For the Assessment And Rating Of Ataxia (SARA) In ataxic stroke patients.Ann Rehabil Med 2011;35:772–80</ref>  
- Spinocerebellar Ataxia<br>- Ataxic Stroke <ref name="Kim et al">Kim BR, Lim JH, Lee SA, Park S, Koh SE, Lee IS, Jung H, Lee J.Usefulness Of the Scale For the Assessment And Rating Of Ataxia (SARA) In ataxic stroke patients.Ann Rehabil Med 2011;35:772–80</ref>  


- Friedreich’s Ataxia <ref name="Burk et al">Bürk K, Mälzig U, Wolf S, Heck S, Dimitriadis K, Schmitz‐Hübsch T, Hering S, Lindig TM, Haug V, Timmann D, Degen I. Comparison of three clinical rating scales in Friedreich ataxia (FRDA). Movement Disorders 2009. 15;24(12):1779-84.</ref> <ref name="Saute et al ">Saute JA, Donis KC, Serrano-Munuera C, Genis D, Ramirez LT, Mazzetti P, Pérez LV, Latorre P, Sequeiros J, Matilla-Dueñas A, Jardim LB. Ataxia rating scales—psychometric profiles, natural history and their application in clinical trials. The Cerebellum. 2012 Jun 1;11(2):488-504.</ref><br>  
- Friedreich’s Ataxia <ref name="Burk et al">Bürk K, Mälzig U, Wolf S, Heck S, Dimitriadis K, Schmitz‐Hübsch T, Hering S, Lindig TM, Haug V, Timmann D, Degen I. Comparison of three clinical rating scales in Friedreich ataxia (FRDA). Movement Disorders 2009. 15;24(12):1779-84.</ref> <ref name="Saute et al">Saute JA, Donis KC, Serrano-Munuera C, Genis D, Ramirez LT, Mazzetti P, Pérez LV, Latorre P, Sequeiros J, Matilla-Dueñas A, Jardim LB. Ataxia rating scales—psychometric profiles, natural history and their application in clinical trials. The Cerebellum. 2012 Jun 1;11(2):488-504.</ref><br>  


== Method of Use  ==
== Method of Use  ==
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[[Image:SARA Pg. 2..png|center]]  
[[Image:SARA Pg. 2..png|center]]  
== Reference<br>  ==
Schmitz-Hübsch T, Tezenas du Montcel S, Baliko L, Berciano J, Boesch S et al. Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology 2006;66:1717-1720.
Schmitz-Hübsch T, Fimmers R, Rakowicz M, Rola R, Zdzienicka E, Fancellu R et al. Responsiveness of different rating instruments in spinocerebellar ataxia patients. Neurology 2010;74:678-84
Weyer A, Abele M, Schmitz-Hübsch T, Schoch B, Frings M et al. Reliability and validity of the Scale for the Assessment and Rating of Ataxia: A Study in 64 ataxia patients. Mov Disord 2007;22:1633-1637.


== Evidence  ==
== Evidence  ==

Revision as of 22:10, 23 February 2016

Original Editor - Ajay Upadhyay

Top Contributors -  

Objective
[edit | edit source]

SARA is a clinical scale developed by Schmitz-Hübsch et al which assesses a range of diffierent impairments in cerebellar ataxia. The scale is made up of 8 items related to gait, stance, sitting, speech, finger-chase test, nose-finger test, fast alternating movements and heel-shin test.[1] Schmitz-Hübsch et al developed the Scale for the Assessment and Rating of Ataxia (SARA) as an alternative to The International Cooperative Ataxia Rating Scale (ICARS). The daily use of ICARS scale in ataxic patients is difficult due to its many assessment items.[2] This new assessment tool has fewer assessment items than the ICARS and therefore has the advantage of easier daily assessment of ataxia. [3]

Intended Population
[edit | edit source]

Currently the following types of Ataxia have been investigated:

- Spinocerebellar Ataxia
- Ataxic Stroke [4]

- Friedreich’s Ataxia [5] [6]

Method of Use[edit | edit source]

The SARA, which Schmitz-Hubsch presented in 2004, is a tool for assessing ataxia. It has eight items with total scores ranging from 0 (no ataxia) to 40 (most severe ataxia). Scores for the eight items range as follows: no ataxia, 1: gait (0-8 points), 2: stance (0-6 points), 3: sitting (0-4 points), 4: speech disturbance (0-6 points), 5: finger chase (0-4 points), 6: nose-finger test (0-4 points), 7: fast alternating hand movement (0-4 points), 8: heel-shin slide (0-4 points), and 40: severe ataxia. For motor activities of the four extremities (items 5-8), assessments are performed bilaterally, and the mean values are used to obtain the total score.  Although the cerebellum is directly involved in the coordination of eye movements, oculomotor functions are not considered, as the validation trials indicated that they are determined by other factors than appendicular and midline ataxia.


SARA.png
SARA Pg. 2..png

Evidence[edit | edit source]

High inter-rater reliability (ICCs5 0.90–0.96)

High test–re-test reliability (ICCs5 0.90–0.96)

High internal consistency (Cronbach’s a50.94)

Good internal structural validity

Links[edit | edit source]

Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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  1. Weyer A, Abele M, Schmitz-Hubsch T, Schoch B, Frings M, Timmann D. Reliability And validity of the scale for the assessment and rating of ataxia: a study in 64 Ataxia patients. Movement Disorders 2007;22:1633–7
  2. Trouillas P, Takayanagi T, Hallett M, Currier RD, Subramony SH, Wessel K, Bryer A, Diener HC, Massaquoi S, Gomez CM, et al. The Ataxia Neuropharmacology Committee of the World Federation of Neurology. International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. J Neurol Sci. 1997;145:205–211.
  3. Schmitz-Hübsch T, du Montcel ST, Baliko L, Berciano J, Boesch S, Depondt C, Giunti P, Globas C, Infante J, Kang JS, et al. Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66:1717–1720.
  4. Kim BR, Lim JH, Lee SA, Park S, Koh SE, Lee IS, Jung H, Lee J.Usefulness Of the Scale For the Assessment And Rating Of Ataxia (SARA) In ataxic stroke patients.Ann Rehabil Med 2011;35:772–80
  5. Bürk K, Mälzig U, Wolf S, Heck S, Dimitriadis K, Schmitz‐Hübsch T, Hering S, Lindig TM, Haug V, Timmann D, Degen I. Comparison of three clinical rating scales in Friedreich ataxia (FRDA). Movement Disorders 2009. 15;24(12):1779-84.
  6. Saute JA, Donis KC, Serrano-Munuera C, Genis D, Ramirez LT, Mazzetti P, Pérez LV, Latorre P, Sequeiros J, Matilla-Dueñas A, Jardim LB. Ataxia rating scales—psychometric profiles, natural history and their application in clinical trials. The Cerebellum. 2012 Jun 1;11(2):488-504.