Parkinson's Lifestyle Medicine - Nutrition and Sleep Hygiene
Original Editor - Thomas Longbottom based on the course by Z Altug
Top Contributors - Thomas Longbottom, Kim Jackson, Tarina van der Stockt, Lucinda hampton and Jess Bell
Introduction[edit | edit source]
Approximately 10 million people around the world are currently living with Parkinson’s Disease.[1] Meta-analysis of worldwide data reveals that the prevalence of Parkinson’s Disease increases with age, quadrupling from a level of almost 0.5% in the seventh decade of life to approximately 2% for those over the age of 80.[2] Parkinson’s is associated with the loss of dopamine-producing neurons in the substantia nigra of the midbrain, and it is typified clinically by resting tremor, rigidity, and bradykinesia along with a number of non-motor features such as anosmia, sleep behavior disorder, depression, autonomic dysfunction, and cognitive dysfunction.[3] The etiology of this disease is not fully understood, but there is some combination of environmental and genetic factors presumed to be causative.[3] Among these are various lifestyle factors such as tobacco use, dietary intake, and physical activity.[4][5]
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Resources[edit | edit source]
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References[edit | edit source]
- ↑ Statistics [Internet]. Parkinson's Foundation. [cited 2021Dec28]. Available from: https://www.parkinson.org/Understanding-Parkinsons/Statistics
- ↑ Pringsheim T, Jette N, Frolkis A, Steeves TDL. The prevalence of Parkinson's disease: A systematic review and meta-analysis. Movement Disorders 2014;29(13):1583–90.
- ↑ 3.0 3.1 Simon DK, Tanner CM, Brundin P. Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology. Clinics in Geriatric Medicine 2020;36(1):1–2.
- ↑ Ritz B, Ascherio A, Checkoway H, Marder KS, Nelson LM, Rocca WA, et al.. Pooled Analysis of Tobacco Use and Risk of Parkinson Disease. Archives of Neurology [Internet] 2007;64(7):990.
- ↑ Paul KC, Chuang Y, Shih I, Keener A, Bordelon Y, Bronstein JM, et al.. The association between lifestyle factors and Parkinson's disease progression and mortality. Movement Disorders 2019;34(1):58–66.
