Extra-Corporeal Membrane Oxygenation: Difference between revisions

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In ECMO, the blood is drained from the vascular system, circulated outside the body by a mechanical pump and then reinfused into the circulation. While the blood is outside the body, hemoglobins become fully saturated with oxygen and carbon dioxide (CO2) is removed from them. <ref>Makdisi G, Wang I wen. Extra Corporeal Membrane Oxygenation (ECMO) review of a lifesaving technology. Journal of Thoracic Disease [Internet]. 2015 Jul; Available from: [[/www.ncbi.nlm.nih.gov/pmc/articles/PMC4522501/|https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522501/]]</ref>
In ECMO, the blood is drained from the vascular system, circulated outside the body by a mechanical pump and then reinfused into the circulation. While the blood is outside the body, hemoglobins become fully saturated with oxygen and carbon dioxide (CO2) is removed from them. <ref>Makdisi G, Wang I wen. Extra Corporeal Membrane Oxygenation (ECMO) review of a lifesaving technology. Journal of Thoracic Disease [Internet]. 2015 Jul; Available from: [[/www.ncbi.nlm.nih.gov/pmc/articles/PMC4522501/|https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522501/]]</ref>


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== Types of ECMO ==
There are two types of ECMO. Veno-arterial (VA) ECMO can be used for heart and lung support, while veno-venous (VV) ECMO is used for lung support only.<ref name=":1">Cui Y, Zhang Y, Dou J, Shi J, Zhao Z, Zhang Z, et al. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982932/#:~:text=VV%20ECMO%20drains%20blood%20from,and%20provides%20complete%20cardiopulmonary%20support. Venovenous vs. Venoarterial Extracorporeal Membrane Oxygenation in Infection-Associated Severe Pediatric Acute Respiratory Distress Syndrome: A Prospective Multicenter Cohort Study]. Frontiers in Pediatrics [Internet]. 2022 Mar 18;10. Available from: [[/doi.org/10.3389/fped.2022.832776|https://doi.org/10.3389/fped.2022.832776]]</ref>
 
==== VA-ECMO ====
VA-ECMO drains the blood from the venous system, reinfuses it into the arterial system and provides complete cardiopulmonary support. <ref name=":1" />
 
==== VV-ECMO ====
VV-ECMO drains the blood from the venous system, reinfuses it into the venous system and provides gas exchange. Unlike VA-ECMO, VV-ECMO does not provide direct cardiac support.<ref name=":1" />
 
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Revision as of 11:22, 30 January 2024

Original Editor - Saud Alghamdi Top Contributors - Saud Alghamdi, Kim Jackson, Vidya Acharya and Ewa Jaraczewska
This article or area is currently under construction and may only be partially complete. Please come back soon to see the finished work! (30/01/2024)

Introduction[edit | edit source]

In 2022, it is estimated that nearly 200,000 patients received Extra-Corporeal Membrane Oxygenation (ECMO).[1] ECMO is a technique that oxygenates the blood outside the body. It’s typically used when conventional ventilation is unable to oxygenate the blood adequately.[2]

It is important to understand that ECMO is a supportive therapy, not a disease-modifying treatment.[3] Similar to a ventilator or a dialysis machine, ECMO doesn't cure the underlying disease but takes over a vital function (oxygenation or blood circulation) when the body's organs are unable to do so adequately.

ECMO is a highly specialised technique that requires the input of intensive care specialists, cardiothoracic surgeons as well as ECMO-trained nurses and perfusion scientists.[2]

How does ECMO work[edit | edit source]

ECMO is a technique that oxygenates the blood outside the body. It’s typically used when conventional ventilation is unable to oxygenate the blood adequately.[2]

In ECMO, the blood is drained from the vascular system, circulated outside the body by a mechanical pump and then reinfused into the circulation. While the blood is outside the body, hemoglobins become fully saturated with oxygen and carbon dioxide (CO2) is removed from them. [4]

Types of ECMO[edit | edit source]

There are two types of ECMO. Veno-arterial (VA) ECMO can be used for heart and lung support, while veno-venous (VV) ECMO is used for lung support only.[5]

VA-ECMO[edit | edit source]

VA-ECMO drains the blood from the venous system, reinfuses it into the arterial system and provides complete cardiopulmonary support. [5]

VV-ECMO[edit | edit source]

VV-ECMO drains the blood from the venous system, reinfuses it into the venous system and provides gas exchange. Unlike VA-ECMO, VV-ECMO does not provide direct cardiac support.[5]


References[edit | edit source]

  1. ECLS ELSOEA. ELSO International Summary of Statistics | ECMO | ECLS [Internet]. Copyright (C) 2023 by Extracorporeal Life Support Organization - ECMO and ECLS. Available from: https://www.elso.org/registry/internationalsummaryandreports/internationalsummary.aspx
  2. 2.0 2.1 2.2 ECMO | Extracorporeal Membrane Oxygenation (ECMO) [Internet]. Royal Papworth Hospital. Available from: https://royalpapworth.nhs.uk/our-services/theatres-and-critical-care/ecmo#:~:text=ECMO%20is%20a%20highly%20specialised,trained%20nurses%20and%20perfusion%20scientists.
  3. Horan M. Extracorporeal membrane oxygenation and mechanical support for the circulation. Anaesthesia & Intensive Care Medicine [Internet]. 2023 Oct 1; Available from: https://doi.org/10.1016/j.mpaic.2023.09.003
  4. Makdisi G, Wang I wen. Extra Corporeal Membrane Oxygenation (ECMO) review of a lifesaving technology. Journal of Thoracic Disease [Internet]. 2015 Jul; Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522501/
  5. 5.0 5.1 5.2 Cui Y, Zhang Y, Dou J, Shi J, Zhao Z, Zhang Z, et al. Venovenous vs. Venoarterial Extracorporeal Membrane Oxygenation in Infection-Associated Severe Pediatric Acute Respiratory Distress Syndrome: A Prospective Multicenter Cohort Study. Frontiers in Pediatrics [Internet]. 2022 Mar 18;10. Available from: https://doi.org/10.3389/fped.2022.832776