Ewing's Sarcoma
Original Editors - Lisa Miville from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
Ewing’s Sarcoma is a malignant primary tumor that can arise in soft tissue or bone. It is actually a family of tumors referred to as Ewing family of tumors (EFT). Although any bone can be invovled, the most common are the pelvis, femur, tibia, ulna and metatarsals.7 It is most common in children and, due to recent availability of aggressive chemotherapy, the 5 year survival rate has increased from 10% to 70%.6
Prevelance[edit | edit source]
Ewing's Sarcoma is the second most common primary malignant bone tumor of children and the fourth more common overall. 80% of these tumors occur in people under the age of 20 and they have been reported in children as young as 5 months. They rarely occur in the African American or Asian population.1,2
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
Chemotherapy, radiation, surgical resection, limb salvage, amputation.1,2
Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
Osteomyelitis - swelling, redness, low grade fever and flu-like symptoms may be present in both conditions.
Case Reports/ Case Studies[edit | edit source]
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Resources
[edit | edit source]
1. Pathophysiology book
6. Goodman C, Snyder T. Differential Diagnosis for Physical Therapists: Screening for Referral. St. Louis, MO: Saunders Elsevier: 2007
2. MedlinePlus
7. Powerpoint from complex patient
Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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