Effects of Ageing on Joints

Original Editor - Wendy Walker

Top Contributors - Lucinda hampton, Wendy Walker, WikiSysop, Lauren Lopez, Tony Lowe and Laura Ritchie  

Introduction[edit | edit source]

No matter how healthy an individual is, as they age their joints will show some changes in mobility, due in part to changes in the connective tissues.
As joint range of movement has a direct effect on posture and movement, this can result in marked alteration of function.

Age related changes in connective tissue[edit | edit source]

Cellular changes[edit | edit source]

Decreased proliferation and altered control of apoptosis (programmed cell death) causes a decrease in effective maintenance of tissue homeostasis[1].

Gross changes[edit | edit source]

  • increased stiffness
  • decreased strength
  • reduction in water content

Sub Heading 3[edit | edit source]

Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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  1. ↑ Freemont AJ, Hoyland JA: Morphology, mechanisms and pathology of musculoskeletal ageing. J Pathol 211:252-259, 2007

 

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