Effects of Ageing on Joints: Difference between revisions

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'''Original Editor '''- Your name will be added here if you created the original content for this page.
'''Original Editor '''- Wendy Walker


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'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}} &nbsp;  
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== Introduction ==
<div>No matter how healthy an individual is, as they age their joints will show some changes in mobility, due in part to changes in the connective tissues.</div><div>As joint range of movement has a direct effect on posture and movement, this can result in marked alteration of function.</div>
== Age related changes in connective tissue ==


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=== Cellular changes ===


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Decreased proliferation and altered control of apoptosis (programmed cell death) causes a decrease in effective maintenance of tissue homeostasis<ref>Freemont AJ, Hoyland JA: Morphology, mechanisms and pathology of musculoskeletal ageing. J Pathol 211:252-259, 2007</ref>.
 
=== Gross changes ===
 
*increased stiffness
*decreased strength
*reduction in water content
 
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== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed])  ==
== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed])  ==
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References will automatically be added here, see [[Adding References|adding references tutorial]].  
References will automatically be added here, see [[Adding References|adding references tutorial]].  


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Revision as of 00:02, 11 June 2014

Original Editor - Wendy Walker

Top Contributors - Lucinda hampton, Wendy Walker, WikiSysop, Lauren Lopez, Tony Lowe and Laura Ritchie  

Introduction[edit | edit source]

No matter how healthy an individual is, as they age their joints will show some changes in mobility, due in part to changes in the connective tissues.
As joint range of movement has a direct effect on posture and movement, this can result in marked alteration of function.

Age related changes in connective tissue[edit | edit source]

Cellular changes[edit | edit source]

Decreased proliferation and altered control of apoptosis (programmed cell death) causes a decrease in effective maintenance of tissue homeostasis[1].

Gross changes[edit | edit source]

  • increased stiffness
  • decreased strength
  • reduction in water content

Sub Heading 3[edit | edit source]

Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

References will automatically be added here, see adding references tutorial.

  1. Freemont AJ, Hoyland JA: Morphology, mechanisms and pathology of musculoskeletal ageing. J Pathol 211:252-259, 2007