Cellulitis

 

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Definition/Description[edit | edit source]

Cellulitis is a localized bacterial skin infection, which typically affects the lower limbs but can occur on any area of skin and underlying subcutaneous tissue  It is characterized by acute onset of redness, inflammation, pain, and swelling of the affected area. Accompanying symptoms include generalized fever, rigors, nausea, and vomiting[1]. The infection is most commonly caused by B-Hemolytic Streptococci bacteria and reoccurs up to 50% of the time in the lower extremity.[1][2] Most individuals diagnosed with cellulitis have a low risk of severe complications but few suffers can have severe sepsis, local gangrene, and/or necrotising fasciitis.[1] 

Prevalence[edit | edit source]

  • 650,000 hospital admissions per year in the United States are due to Cellulitis.[3]
  • When hospitalized, patients with recurrent cellulitis require longer hospitalizations relative to nonrelapsing cellulitis patients.[3]
  • From 1998-2006, 10% of all infectious-disease hospitalizations were related to Cellulitis[3]
  • 22-49% of patients who have cellulitis report at least one previous episode[3]
  • Recurrences, typically in the same location, occur approximately 14% of cellulitis cases within 1 year and in 45% of cases within 3 years[3]


Characteristics/Clinical Presentation[edit | edit source]

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Associated Co-morbidities[edit | edit source]

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Medications[edit | edit source]

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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

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Etiology/Causes[edit | edit source]

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Systemic Involvement[edit | edit source]

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Medical Management (current best evidence)[edit | edit source]

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Physical Therapy Management (current best evidence)[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Case Reports/ Case Studies[edit | edit source]

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Resources
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Recent Related Research (from <a href="http://www.ncbi.nlm.nih.gov/pubmed/">Pubmed</a>)[edit | edit source]

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References[edit | edit source]

  1. 1.0 1.1 1.2 Mason JM, Thomas KS, Crook AM, Foster KA, Chalmers JR, et al. Prophylactic Antibiotics to Prevent Cellulitis of the Leg: Economic Analysis of the PATCH I &amp;amp; II Trials. PLoS ONE. 2014;9(2):e82694 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082694 (accessed 28 Feb 2017)
  2. Tsai C-YL, Calvin MK, Chung C, Susan Shin-Jung L, Yao-Shen C, Hung C. Development of a prediction model for bacteremia in hospitalized adults with cellulitis to aid in the efficient use of blood cultures: a retrospective cohort study. BMC Infectious Diseases. 2016;16(1):581. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-016-1907-2 (accessed 27 Feb 2017).
  3. 3.0 3.1 3.2 3.3 3.4 Raff AB, Kroshinsky D. Cellulitis: A Review. JAMA. 2016;316(3):325-37. http://jamanetwork.com/pdfaccess.ashx?url=/data/journals/jama/935437/ (accessed 27 Feb 2017).