Cellulitis

 

Welcome to <a href="Pathophysiology of Complex Patient Problems">PT 635 Pathophysiology of Complex Patient Problems</a> This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Original Editors - <a href="Pathophysiology of Complex Patient Problems">Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.</a>

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Definition/Description[edit | edit source]

Cellulitis is a localized bacterial skin infection, which typically affects the lower limbs but can occur on any area of skin and underlying subcutaneous tissue  It is characterized by acute onset of redness, inflammation, pain, and swelling of the affected area. Accompanying symptoms include generalized fever, rigors, nausea, and vomiting[1] (1). The infection is most commonly caused by B-Hemolytic Streptococci bacteria and reoccurs up to 50% of the time in the lower extremity (1, 3). Most individuals diagnosed with cellulitis have a low risk of severe complications but few suffers can have severe sepsis, local gangrene, and/or necrotising fasciitis. (1)

Prevalence[edit | edit source]

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Characteristics/Clinical Presentation[edit | edit source]

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Associated Co-morbidities[edit | edit source]

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Medications[edit | edit source]

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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

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Etiology/Causes[edit | edit source]

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Systemic Involvement[edit | edit source]

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Medical Management (current best evidence)[edit | edit source]

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Physical Therapy Management (current best evidence)[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Case Reports/ Case Studies[edit | edit source]

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Resources
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References[edit | edit source]

  1. Mason JM, Thomas KS, Crook AM, Foster KA, Chalmers JR, et al. Prophylactic Antibiotics to Prevent Cellulitis of the Leg: Economic Analysis of the PATCH I & II Trials. PLoS ONE. 2014;9(2):e82694 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082694 (accessed 28 Feb 2017)


[1] Mason JM, Thomas KS, Crook AM, Foster KA, Chalmers JR, et al. Prophylactic Antibiotics to Prevent Cellulitis of the Leg: Economic Analysis of the PATCH I & II Trials. PLoS ONE. 2014;9(2):e82694 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082694 (accessed 28 Feb 2017).

[2] Kilburn SA, Featherstone P, Higgins B, Brindle R. Interventions for cellulitis and erysipelas. (Cochrane review). Cochrane Database Syst Rev. 2010(6):CD004299.

[3] Tsai C-YL, Calvin MK, Chung C, Susan Shin-Jung L, Yao-Shen C, Hung C. Development of a prediction model for bacteremia in hospitalized adults with cellulitis to aid in the efficient use of blood cultures: a retrospective cohort study. BMC Infectious Diseases. 2016;16(1):581. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-016-1907-2 (accessed 27 Feb 2017).
[4] Raff AB, Kroshinsky D. Cellulitis: A Review. JAMA. 2016;316(3):325-37.
http://jamanetwork.com/pdfaccess.ashx?url=/data/journals/jama/935437/ (accessed 27 Feb 2017).

[5] Medscape. Cellulitis. http://emedicine.medscape.com/article/214222-overview (accessed 27 Feb 2017)

[6] Knepper BC, Jason Moore S, Saveli CC, Pawlowski SW, Perlman DM, McCollister BD, Burman WJ. Diabetes Mellitus and Skin Infections. J. Hosp. Med 2014;12;788-794. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256165/ (accessed 15 March 2017).
[7] McNamara DR, Tleyjeh IM, Berbari EF, Lahr BD, Martinez J, Mirzoyev SA, Baddour LM. A predictive model of recurrent lower extremity cellulitis in a population-based cohort. Arch Intern Med. 2007;167(7):709-715 http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/412163 (accessed 15 March 2017).



  1. Mason JM, Thomas KS, Crook AM, Foster KA, Chalmers JR, et al. Prophylactic Antibiotics to Prevent Cellulitis of the Leg: Economic Analysis of the PATCH I &amp;amp;amp; II Trials. PLoS ONE. 2014;9(2):e82694 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082694 (accessed 28 Feb 2017).
  2. Kilburn SA, Featherstone P, Higgins B, Brindle R. Interventions for cellulitis and erysipelas. (Cochrane review). Cochrane Database Syst Rev. 2010(6):CD004299.
  3. Tsai C-YL, Calvin MK, Chung C, Susan Shin-Jung L, Yao-Shen C, Hung C. Development of a prediction model for bacteremia in hospitalized adults with cellulitis to aid in the efficient use of blood cultures: a retrospective cohort study. BMC Infectious Diseases. 2016;16(1):581. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-016-1907-2 (accessed 27 Feb 2017).
  4. Raff AB, Kroshinsky D. Cellulitis: A Review. JAMA. 2016;316(3):325-37.fckLR http://jamanetwork.com/pdfaccess.ashx?url=/data/journals/jama/935437/ (accessed 27 Feb 2017).
  5. Medscape. Cellulitis. http://emedicine.medscape.com/article/214222-overview (accessed 27 Feb 2017)
  6. Knepper BC, Jason Moore S, Saveli CC, Pawlowski SW, Perlman DM, McCollister BD, Burman WJ. Diabetes Mellitus and Skin Infections. J. Hosp. Med 2014;12;788-794. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256165/ (accessed 15 March 2017).
  7. McNamara DR, Tleyjeh IM, Berbari EF, Lahr BD, Martinez J, Mirzoyev SA, Baddour LM. A predictive model of recurrent lower extremity cellulitis in a population-based cohort. Arch Intern Med. 2007;167(7):709-715 http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/412163 (accessed 15 March 2017).