Sequential Organ Failure Assessment Score

div class="noeditbox">This article or area is currently under construction and may only be partially complete. Please come back soon to see the finished work! (29/12/2022)

Original Editor - Uchechukwu Chukwuemeka

Top Contributors - Uchechukwu Chukwuemeka, Lucinda hampton and Kim Jackson  

Introduction

The sequential organ failure assessment score (SOFA score), formerly termed the sepsis-related organ failure assessment score, is used to monitor a patient's condition while they are in an intensive care unit (ICU) in order to gauge how well their organs are functioning or how quickly they are failing. Although many different scoring systems have been created, the Sequential Organ Failure Assessment (SOFA) score is now the most used in real-world applications . In contrast to other scores (e.g. Multiple Organ Dysfunction Score and Logistic Organ Dysfunction System ), which established models using statistical techniques, it was developed by consensus.

Objective

It is employed to keep an eye on a patient's condition while in an intensive care unit (ICU) to determine how well or rapidly their organs are failing, as well as evaluate the impact of new therapies on the progression of organ dysfunction/failure. This could be used to characterize patients at entry (and even serve as an entry criterion) or to evaluate treatment effects. The SOFA score does not distinguish between the impacts of acute organ dysfunction associated with critical illness and persistent organ failure occurring owing to underlying disease.

Intended Population

The SOFA score is intended for critically ill patients and/or patients in the intensive care unit (ICU) to better understand the natural history of organ dysfunction/failure and the interrelationship between organ failure.

Method of Use

Six distinct scores, one for each of the respiratory, cardiovascular, hepatic, coagulation, renal, and neurological systems (central nervous system)make up the final result. Each organ system received a score ranging from 0 (normal) to 4 (most abnormal), with a minimum SOFA score of 0 and a maximum SOFA score of 24. The table below summarizes the scoring of SOFA.

There is also the fast SOFA score (qSOFA), a shortened version of SOFA which aids medical professionals in determining the likelihood of morbidity and mortality as a result of sepsis using four variables as depicted in the table below

Quick SOFA
Is the patient in the ICU?	Yes      No
Altered Mentation	Yes      No
Respiratory rate (breaths per minute)	(0 to 60)
Systolic blood pressure (mmHg)	(0 to 300)

The SOFA Score
Score	Central nervous system Glasgow Coma Score	Respiratory system PaO 2/FiO2, mmHg	Cardiovascular system Mean arterial pressure(mmHg) or Vasopressors administered (μg/kg/min)	Coagulation Platelets x 103/mm3	Hepatic function Bilirubin, mg/dl(μmol/L)	Renal function Creatinine, mg/dl(μmol/L) or Urine output (ml/day)
0	15	</=400	MAP >/=70	>/=150	<1.2 (<20)	<1.2 (<110)
1	13-14	<400	MAP <70	<150	1.2- 1.9 (20-32)	1.2- 1.9 (110-170)
2	10-12	<300	Dopamine </=5 or dobutamine (any dose)	<100	2.0- 5.9 (33-101)	2.0- 3.4 (171-299)
3	6-9	<200 with ventilatory support	Dopamine > 5 or epinephrine </=0.1 or norepinephrine </=0.1	<50	6.0-11.9 (102-204)	3.5-4.9 (300 - 440) or < 500
4	<6	<100 with ventilatory support	Dopamine > 15 or epinephrine > 0.1 or norepinephrine > 0.1	<20	>12.0 (>204)	>5.0 ( > 440) or <200

Resources

• bulleted list
• x

or

1. numbered list
2. x

References

.