Myositis Ossificans

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton, Kim Jackson and Ahmed M Diab  

Introduction[edit | edit source]

Myositis ossificans (MO) is the most common form of heterotopic ossification (HO), usually within large muscles.[1]

  • Some doctors view these MO and as two points on the same line. They are similar problems that cause pain, local signs of inflammation, and loss of motion.
  • In both cases, bone forms in and around soft tissue (usually muscle). Myositis ossificans (MO) occurs after trauma to the muscle or a broken bone. New bone cells form between the torn muscle fibers. This happens most often around the elbow or thigh. Children and young adults are affected most often[2].

Epidemiology[edit | edit source]

Most cases of myositis ossificans occur as a result of trauma, and thus, the primary demographic is young adults. Another group which is especially prone to myositis ossificans are paraplegics, usually without evidence of trauma.[1]

Clinical presentation[edit | edit source]

Typically presents as a painful, tender, enlarging mass, which in 80% of cases is located in large muscles of the extremities, often following recognized local trauma, although a definite traumatic event is not always recalled.

In the case of paraplegics, recognized episodes of trauma are often absent, and the disease occurs particularly around the knees and hips[1].

Pathology[edit | edit source]

Myositis ossificans is essentially metaplasia of the intramuscular connective tissue resulting in extraosseous bone formation (without inflammation).

Unfortunately, the histologically of myositis ossificans can appear similar to osteosarcoma, and thus, can lead to inappropriate management.[1]

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References[edit | edit source]