Chronic Kidney Disease

This article or area is currently under construction and may only be partially complete. Please come back soon to see the finished work! (20/10/2020)

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton, Bruno Serra, Vidya Acharya and Kim Jackson  

Introduction

Chronic kidney disease (CKD):

• A progressive loss of glomerular function caused by a long-standing renal parenchymal disease. It is present when the glomerular filtration rate (GFR) is less than 60 ml/min/1.73 m2 for three consecutive months or greater than or equal to this value in patients with a kidney damage that is present for three or more months.
• A non-communicable disease usually caused by diabetes and hypertension
• Often involves a progressive loss of kidney function necessitating renal replacement therapy (dialysis or transplantation). When a patient needs renal replacement therapy, the condition is called end-stage renal disease (ESRD).

Function

Filter the blood to remove excess water, minerals, and waste products of protein metabolism, producing urine in the process

Kidneys are involved in

• Blood pressure regulation
• Regulation of body fluid volume, osmolality and pH
• Vitamin D and red blood cell (RBC) production

Renal function tests

• Estimated glomerular filtration rate (eGFR)
• Electrolytes
• Blood urea nitrogen (BUN) (urea in the UK)
• Creatinine levels

Resources

• bulleted list
• x

or

1. numbered list
2. x