Pain Facilitation and Inhibition
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Tips for writing this page:
- Define and describe the differences between faciliatatory and inhibitory pathways, incluing their brain sites and neurotransmitters
- Explain and describe how these pathways can be activated by non-pharmacological agents.
Original Editor - Manisha Shrestha
Top Contributors - Manisha Shrestha, Lucinda hampton, Jo Etherton, Kim Jackson, Lauren Lopez, Tolulope Adeniji and Kirenga Bamurange Liliane
ascending and descending tracts for pain pathways.Ascending tract-lateral spinothalamic tract. 1st order neuron from pheripheral tissue ( prostaglandins) to dorsal horn of spinal cord(substania gelatinosa). neurotransmitter is Substance P. 2nd order neuron from sustania gelatinosa to thalamus . then 3rd order neuron from thalamus to cortex (primary and secondary somatosensory cortex (S1 and S2, respectively), anterior- and mid-cingulate cortex (ACC and MCC, respectively) and insula.
Facilitatory Pathways[edit | edit source]
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Inhibitory Pathways[edit | edit source]
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Sub Heading 3[edit | edit source]
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References[edit | edit source]
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- ↑ Armando Hasudungan. PAIN! Physiology - The Ascending Pathway, Descending Pain Pathway and the Substantia Gelatinosa. Available From: https://www.youtube.com/watch?v=5c8maFAhqIc [last accessed 22/2/2020]
