Gilbert's Syndrome
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Top Contributors - J.Dylan James, Elaine Lonnemann, WikiSysop, Kim Jackson and 127.0.0.1
Definition/Description[edit | edit source]
Gilbert’s syndrome is a benign liver condition that is characterized by elevated levels of bilirubin in the blood.([1],[2]) Bilirubin is produced by the breakdown of red blood cells and is able to be removed from the body after the liver converts it from unconjugated bilirubin to conjugated bilirubin.([3],[4],[5]) In individuals with Gilbert’s syndrome, there is a buildup of unconjugated bilirubin in the liver as a result of a genetic mutation of the enzyme UDP-glucuronosyltransferase 1A isoform 1 (UGT1A1), which is important in bilirubin metabolism.([6],[7]) The buildup of bilirubin is particularly evident after starvation, exertion, infection, consumption of alcohol, or dehydration.(5) Bilirubin levels fluctuate and rarely increase to levels that cause jaundice.([8])
Prevalence[edit | edit source]
add text here
Characteristics/Clinical Presentation[edit | edit source]
add text here
Associated Co-morbidities[edit | edit source]
add text here
Medications[edit | edit source]
add text here
Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
add text here
Etiology/Causes[edit | edit source]
add text here
Systemic Involvement[edit | edit source]
add text here
Medical Management (current best evidence)[edit | edit source]
add text here
Physical Therapy Management (current best evidence)[edit | edit source]
add text here
Differential Diagnosis[edit | edit source]
add text here
Case Reports/ Case Studies[edit | edit source]
add links to case studies here (case studies should be added on new pages using the case study template)
Resources
[edit | edit source]
add appropriate resources here
Recent Related Research (from Pubmed)[edit | edit source]
see tutorial on Adding PubMed Feed
Extension:RSS -- Error: Not a valid URL: addfeedhere|charset=UTF-8|short|max=10