Cytomegalovirus (CMV) Infection

 

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Description[edit | edit source]

Cytomegalovirus (CMV) Infection, also known as herpesvirus type 5, is a common virus belonging to the herpes family that affects a variety of individuals across the lifespan[1]. It is currently the leading cause of congenital infections in the world, and can cause long term consequences such as hearing loss, visual deficits, and cognitive delays[2][3]. It is frequently acquired in late childhood or early adulthood, and is rarely symptomatic, except in the immunocompromised.


[edit | edit source]

Prevalence[edit | edit source]

Reported incidence of CMV varies. Recent evidence suggests that one percent of newborns have the virus, as well as eighty percent of people over 35 years of age[1]. Other studies report that 50-80% of people are infected with the virus, and up to 90% or more in developing countries[2]. After infection, the virus may remain latent within monocytes, frequently causing it to be difficult to detect[4]. Therefore, true prevalence may be different than numbers reported.

Characteristics/Clinical Presentation[edit | edit source]

add text here

Associated Co-morbidities[edit | edit source]

add text here

Medications[edit | edit source]

add text here

Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

add text here

Etiology/Causes[edit | edit source]

add text here

Systemic Involvement[edit | edit source]

add text here

Medical Management (current best evidence)[edit | edit source]

add text here

Physical Therapy Management (current best evidence)[edit | edit source]

add text here

Differential Diagnosis[edit | edit source]

add text here

Case Reports/ Case Studies[edit | edit source]

add links to case studies here (case studies should be added on new pages using the case study template)

Resources
[edit | edit source]

add appropriate resources here

Recent Related Research (from Pubmed)[edit | edit source]

see tutorial on Adding PubMed Feed

Extension:RSS -- Error: Not a valid URL: addfeedhere|charset=UTF-8|short|max=10

References[edit | edit source]

see adding references tutorial.

  1. 1.0 1.1 Goodman C, Snyder T. Differential Diagnosis for Physical Therapists: Screening for Referral. 5th ed. St. Louis, MO: Elsevier; 2013: 336-337.
  2. 2.0 2.1 Cytomegalovirus (CMV). https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv (accessed 04 March 2016).
  3. Dollard S, Grosse S, Ross D. New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection. Reviews In Medical Virology [serial on the Internet]. (2007, Sep), [cited April 4, 2016]; 17(5): 355-363. Available from: MEDLINE.
  4. Guo R, Gebreab F, Tang E, Piao Z, Lee S, Perez M. Cutaneous Ulcer as Leading Symptom of Systemic Cytomegalovirus Infection. Case Reports In Infectious Diseases [serial on the Internet]. (2015, Feb 16), [cited April 4, 2016]; 20151-4. Available from: Academic Search Complete.