Neck Hump: Difference between revisions
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# Cervical Lipodystrophy: Refers to a metabolic change seen in [[Human Immunodeficiency Virus (HIV)|HIV]]-infected patients receiving highly active antiretroviral therapy. Due to lipohypertrophy, localized abnormal fat accumulation may occur in the dorso-cervical area. <ref>Carrese E, Morandi U, Stefani A, Aramini B. [https://www.sciencedirect.com/science/article/pii/S221026121930402X#bib0020 Total thyroidectomy in HIV positive patient with buffalo hump and taurine neck]. International Journal of Surgery Case Reports. 2019 Jan 1;61:64-6.</ref> | # Cervical Lipodystrophy: Refers to a metabolic change seen in [[Human Immunodeficiency Virus (HIV)|HIV]]-infected patients receiving highly active antiretroviral therapy. Due to lipohypertrophy, localized abnormal fat accumulation may occur in the dorso-cervical area. <ref>Carrese E, Morandi U, Stefani A, Aramini B. [https://www.sciencedirect.com/science/article/pii/S221026121930402X#bib0020 Total thyroidectomy in HIV positive patient with buffalo hump and taurine neck]. International Journal of Surgery Case Reports. 2019 Jan 1;61:64-6.</ref> | ||
# Dowager’s hump: It refers to the curvature with a [[Cobb Angle|Cobb angle]] of more than 40 degrees in [[Thoracic Hyperkyphosis|hyperkyphosis]]. <ref name=":0">Chau C, Chu EC, Huang KH, Tam D, Cheung G. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478669/ Remission of Dowager’s hump by manipulative correction of spinal alignment: a case report]. Journal of Medicine and Life. 2023 Jun;16(6):957.</ref> It can be due to muscle weakness or sensory deficits <ref>Chu EC, Wong AY. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636150/ Cervicogenic dizziness in an 11-year-old girl: a case report]. Adolescent Health, Medicine and Therapeutics. 2021 Nov 26:111-6.</ref> and if left untreated can lead to functional limitations, increased risk of falls and vertebral fractures, and low quality of life. <ref name=":0" /> | # Dowager’s hump: It refers to the curvature with a [[Cobb Angle|Cobb angle]] of more than 40 degrees in [[Thoracic Hyperkyphosis|hyperkyphosis]]. <ref name=":0">Chau C, Chu EC, Huang KH, Tam D, Cheung G. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478669/ Remission of Dowager’s hump by manipulative correction of spinal alignment: a case report]. Journal of Medicine and Life. 2023 Jun;16(6):957.</ref> It can be due to muscle weakness or sensory deficits <ref>Chu EC, Wong AY. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636150/ Cervicogenic dizziness in an 11-year-old girl: a case report]. Adolescent Health, Medicine and Therapeutics. 2021 Nov 26:111-6.</ref> and if left untreated can lead to functional limitations, increased risk of falls and vertebral fractures, and low quality of life. <ref name=":0" /> | ||
# [[Cushing's Syndrome]] | # [[Cushing's Syndrome]]: One of the signs of this syndrome is supraclavicular/dorsocervical fat pad (buffalo hump) with a prevalence rate of 50%. <ref>Savas M, Mehta S, Agrawal N, van Rossum EF, Feelders RA. [https://onlinelibrary.wiley.com/doi/abs/10.1111/jne.13114 Approach to the patient: diagnosis of Cushing syndrome]. The Journal of Clinical Endocrinology & Metabolism. 2022 Nov 1;107(11):3162-74.</ref> | ||
# Madelung's disease: Also known as Launois-Bensaude syndrome <ref>Jang N, Shin HW, Kim J, Yoon KC. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644345/ A case report of Madelung’s disease. Archives of Craniofacial Surgery]. 2020 Oct;21(5):305.</ref>, is a rare disorder of adipose metabolism | # Madelung's disease: Also known as Launois-Bensaude syndrome <ref>Jang N, Shin HW, Kim J, Yoon KC. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644345/ A case report of Madelung’s disease. Archives of Craniofacial Surgery]. 2020 Oct;21(5):305.</ref>, is a rare disorder of adipose metabolism and refers to multiple, symmetrical lipomatosis / benign symmetric lipomatosis. <ref>Tsilivigkos C, Mastronikolis S, Lygeros S, Tsilimpoti D, Papadas T. [https://onlinelibrary.wiley.com/doi/full/10.1002/ccr3.4288 Multiple symmetric lipomatosis (Madelung's disease) with symptoms and signs of hypertension, lipodystrophy, and dyspnea: A case report and literature review]. Clinical Case Reports. 2021 Jun;9(6):e04288.</ref><ref>Liu SZ, Zhou X, Wang YP, Liu Y, Song A. The Madelung’s disease and the buffalo hump sign. QJM: An International Journal of Medicine. 2020 Mar 1;113(3):219-.</ref> Nonencapsulated lipomas (fatty masses) can present in different parts of the body, including the neck. <ref>Nisi G, Sisti A. Madelung's disease. New England Journal of Medicine. 2016;374(6):572-.</ref> | ||
# [[Osteoporosis]] | # [[Osteoporosis]]: One of the clinical symptoms of osteoporosis in older adults is dowager’s hump. <ref>Zhang Q, Cai W, Wang G, Shen X. Prevalence and contributing factors of osteoporosis in the elderly over 70 years old: an epidemiological study of several community health centers in Shanghai. Ann Palliat Med. 2020 Mar 1;9(2):231-8.</ref> | ||
# Obesity | # Obesity: A study <ref>Gün E, Uzun H, Bolu S, Arslanoğlu İ, Kocabay K. Serum 25-hydroxyvitamin D is associated with insulin resistance independently of obesity in children ages 5–17. Primary care diabetes. 2020 Dec 1;14(6):741-6.</ref> showed a meaningful difference between the obese and control group with more cases of adipomastia, and buffalo hump seen in the obese group. | ||
# Genetics | # Genetics: Although any specific gene to cause buffalo hump has not been declared, it is known that some people may have a genetic predisposition to obesity and fat accumulation in certain areas of the body, thus having buffalo hump. | ||
== Treatment == | == Treatment == |
Revision as of 20:29, 12 October 2023
This article or area is currently under construction and may only be partially complete. Please come back soon to see the finished work! (12/10/2023)
Original Editor - Sehriban Ozmen
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Definition[edit | edit source]
The neck hump, also called buffalo hump, is a postural change that develops in the dorso-cervical area due to different causes such as postural issues, some of diseases, medications, obesity and genetic factors.
Clinically Relevant Anatomy[edit | edit source]
Aetiology[edit | edit source]
- Cervical Lipodystrophy: Refers to a metabolic change seen in HIV-infected patients receiving highly active antiretroviral therapy. Due to lipohypertrophy, localized abnormal fat accumulation may occur in the dorso-cervical area. [1]
- Dowager’s hump: It refers to the curvature with a Cobb angle of more than 40 degrees in hyperkyphosis. [2] It can be due to muscle weakness or sensory deficits [3] and if left untreated can lead to functional limitations, increased risk of falls and vertebral fractures, and low quality of life. [2]
- Cushing's Syndrome: One of the signs of this syndrome is supraclavicular/dorsocervical fat pad (buffalo hump) with a prevalence rate of 50%. [4]
- Madelung's disease: Also known as Launois-Bensaude syndrome [5], is a rare disorder of adipose metabolism and refers to multiple, symmetrical lipomatosis / benign symmetric lipomatosis. [6][7] Nonencapsulated lipomas (fatty masses) can present in different parts of the body, including the neck. [8]
- Osteoporosis: One of the clinical symptoms of osteoporosis in older adults is dowager’s hump. [9]
- Obesity: A study [10] showed a meaningful difference between the obese and control group with more cases of adipomastia, and buffalo hump seen in the obese group.
- Genetics: Although any specific gene to cause buffalo hump has not been declared, it is known that some people may have a genetic predisposition to obesity and fat accumulation in certain areas of the body, thus having buffalo hump.
Treatment[edit | edit source]
Resources[edit | edit source]
References[edit | edit source]
- ↑ Carrese E, Morandi U, Stefani A, Aramini B. Total thyroidectomy in HIV positive patient with buffalo hump and taurine neck. International Journal of Surgery Case Reports. 2019 Jan 1;61:64-6.
- ↑ 2.0 2.1 Chau C, Chu EC, Huang KH, Tam D, Cheung G. Remission of Dowager’s hump by manipulative correction of spinal alignment: a case report. Journal of Medicine and Life. 2023 Jun;16(6):957.
- ↑ Chu EC, Wong AY. Cervicogenic dizziness in an 11-year-old girl: a case report. Adolescent Health, Medicine and Therapeutics. 2021 Nov 26:111-6.
- ↑ Savas M, Mehta S, Agrawal N, van Rossum EF, Feelders RA. Approach to the patient: diagnosis of Cushing syndrome. The Journal of Clinical Endocrinology & Metabolism. 2022 Nov 1;107(11):3162-74.
- ↑ Jang N, Shin HW, Kim J, Yoon KC. A case report of Madelung’s disease. Archives of Craniofacial Surgery. 2020 Oct;21(5):305.
- ↑ Tsilivigkos C, Mastronikolis S, Lygeros S, Tsilimpoti D, Papadas T. Multiple symmetric lipomatosis (Madelung's disease) with symptoms and signs of hypertension, lipodystrophy, and dyspnea: A case report and literature review. Clinical Case Reports. 2021 Jun;9(6):e04288.
- ↑ Liu SZ, Zhou X, Wang YP, Liu Y, Song A. The Madelung’s disease and the buffalo hump sign. QJM: An International Journal of Medicine. 2020 Mar 1;113(3):219-.
- ↑ Nisi G, Sisti A. Madelung's disease. New England Journal of Medicine. 2016;374(6):572-.
- ↑ Zhang Q, Cai W, Wang G, Shen X. Prevalence and contributing factors of osteoporosis in the elderly over 70 years old: an epidemiological study of several community health centers in Shanghai. Ann Palliat Med. 2020 Mar 1;9(2):231-8.
- ↑ Gün E, Uzun H, Bolu S, Arslanoğlu İ, Kocabay K. Serum 25-hydroxyvitamin D is associated with insulin resistance independently of obesity in children ages 5–17. Primary care diabetes. 2020 Dec 1;14(6):741-6.